Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone
TL;DR: Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone (CAS 76960-26-4) is a chemical compound with molecular formula C30H40ClN5O6 and molecular weight 601.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-2-[[(3S)-1-chloro-5-methyl-2-oxohexan-3-yl]amino]-3-phenylpropanoyl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide
Also Known As: Tagplcmk, Daleck, Tyr-D-ala-gly-phe-leu-chloromethyl ketone, Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone, Ala(2)-leu(5)-enkephalin chloromethyl ketone
| Molecular Formula | C30H40ClN5O6 |
|---|---|
| Molecular Weight | 601.27 g/mol |
| LogP | 0.9492 |
| Topological Polar Surface Area | 179.72 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 16 |
| Exact Mass | 601.2667 |
| Heavy Atoms | 42 |
| Complexity | 1208.43 |
Chemical Identifiers
| CAS Number | 76960-26-4 |
|---|---|
| SMILES | C[C@H](C(=O)NCC(=O)NC(=O)[C@H](CC1=CC=CC=C1)N[C@@H](CC(C)C)C(=O)CCl)NC(=O)[C@H](CC2=CC=C(C=C2)O)N |
Product Overview
Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone (CAS 76960-26-4), with molecular formula C30H40ClN5O6 and molecular weight 601.27 g/mol. IUPAC: (2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-2-[[(3S)-1-chloro-5-methyl-2-oxohexan-3-yl]amino]-3-phenylpropanoyl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide.
Chemical Property Profile of Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone
Property Insights of Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone
The XLogP value of 0.9492 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone. The TPSA of 179.72 Ų indicates high polarity, suggesting Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone has 6 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone?
The CAS number of Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone is 76960-26-4.
What is the molecular formula of Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone?
The molecular formula of Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone is C30H40ClN5O6.
What is the molecular weight of Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone?
The molecular weight of Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone is 601.27 g/mol.
Where can I buy Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone?
You can request a quote for Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone?
Yes, KEHONG BIO provides custom synthesis services for Tyrosyl-alanyl-glycyl-phenylalanyl-leucine chloromethyl ketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.