Chlorocamptothecin structure

Chlorocamptothecin

TL;DR: Chlorocamptothecin (CAS 7691-05-6) is a chemical compound with molecular formula C20H15ClN2O3 and molecular weight 366.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

19-chloro-19-ethyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

Also Known As: Chlorocamptothecin, (S)-4-Chloro-4-ethyl-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-chloro-4-ethyl-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-chloro-4-ethyl-, (S)-, 1H-PYRANO(3',4':6,7)INDOLIZINO[1,2-B]QUINOLINE-3,14(4H,12H)-DIONE,4-CHLORO-4-ETHYL-,(S)-

CAS: 7691-05-6
Molecular Formula C20H15ClN2O3
Molecular Weight 366.08 g/mol
LogP 2.3
Topological Polar Surface Area 59.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 1
Exact Mass 366.07712
Heavy Atoms 26
Complexity 745.0

Chemical Identifiers

CAS Number 7691-05-6
SMILES CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)Cl
InChIKey YFCMUKGFTGDDDG-UHFFFAOYSA-N

Product Overview

Chlorocamptothecin (CAS 7691-05-6), with molecular formula C20H15ClN2O3 and molecular weight 366.08 g/mol. IUPAC: 19-chloro-19-ethyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Chlorocamptothecin

XLogP
2.3
TPSA (Topological Polar Surface Area)
59.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
1
Heavy Atoms
26
Complexity
745.0
Exact Mass
366.07712
Monoisotopic Mass
366.07712
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Chlorocamptothecin

The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Chlorocamptothecin. With a topological polar surface area (TPSA) of 59.5 Ų, Chlorocamptothecin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Chlorocamptothecin has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Chlorocamptothecin?

The CAS number of Chlorocamptothecin is 7691-05-6.

What is the molecular formula of Chlorocamptothecin?

The molecular formula of Chlorocamptothecin is C20H15ClN2O3.

What is the molecular weight of Chlorocamptothecin?

The molecular weight of Chlorocamptothecin is 366.08 g/mol.

Where can I buy Chlorocamptothecin?

You can request a quote for Chlorocamptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Chlorocamptothecin?

Yes, KEHONG BIO provides custom synthesis services for Chlorocamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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