Thyrotropin releasing hormone chloromethyl ketone
TL;DR: Thyrotropin releasing hormone chloromethyl ketone (CAS 76819-95-9) is a chemical compound with molecular formula C17H22ClN5O4 and molecular weight 395.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-[(2S)-2-(2-chloroacetyl)pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Trh-cmk, Thyrotropin releasing hormone chloromethyl ketone, 2-Pyrrolidinecarboxamide, N-(2-(2-(chloroacetyl)-1-pyrrolidinyl)-1-(1H-imidazol-4-ylmethyl)-2-oxoethyl)-5-oxo-, (2S-(2R*(R*(R*))))-, (2S)-N-[(2S)-1-[(2S)-2-(2-chloroacetyl)pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide, (2S)-N-[(2S)-1-[(2S)-2-(2-chloroacetyl)pyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
| Molecular Formula | C17H22ClN5O4 |
|---|---|
| Molecular Weight | 395.14 g/mol |
| LogP | -1.0 |
| Topological Polar Surface Area | 124.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 395.13602 |
| Heavy Atoms | 27 |
| Complexity | 616.0 |
Chemical Identifiers
| CAS Number | 76819-95-9 |
|---|---|
| SMILES | C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)CCl |
| InChIKey | IUYWTEQKCXPSLN-AVGNSLFASA-N |
Product Overview
Thyrotropin releasing hormone chloromethyl ketone (CAS 76819-95-9), with molecular formula C17H22ClN5O4 and molecular weight 395.14 g/mol. IUPAC: (2S)-N-[(2S)-1-[(2S)-2-(2-chloroacetyl)pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of Thyrotropin releasing hormone chloromethyl ketone
Property Insights of Thyrotropin releasing hormone chloromethyl ketone
The XLogP value of -1.0 indicates that Thyrotropin releasing hormone chloromethyl ketone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 124.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Thyrotropin releasing hormone chloromethyl ketone. Following Lipinski's Rule of Five, Thyrotropin releasing hormone chloromethyl ketone has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thyrotropin releasing hormone chloromethyl ketone?
The CAS number of Thyrotropin releasing hormone chloromethyl ketone is 76819-95-9.
What is the molecular formula of Thyrotropin releasing hormone chloromethyl ketone?
The molecular formula of Thyrotropin releasing hormone chloromethyl ketone is C17H22ClN5O4.
What is the molecular weight of Thyrotropin releasing hormone chloromethyl ketone?
The molecular weight of Thyrotropin releasing hormone chloromethyl ketone is 395.14 g/mol.
Where can I buy Thyrotropin releasing hormone chloromethyl ketone?
You can request a quote for Thyrotropin releasing hormone chloromethyl ketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thyrotropin releasing hormone chloromethyl ketone?
Yes, KEHONG BIO provides custom synthesis services for Thyrotropin releasing hormone chloromethyl ketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.