Hydroxyterfenadine structure

Hydroxyterfenadine

TL;DR: Hydroxyterfenadine (CAS 76815-56-0) is a chemical compound with molecular formula C32H41NO3 and molecular weight 487.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]-1-[4-(1-hydroxy-2-methylpropan-2-yl)phenyl]butan-1-ol

Also Known As: hydroxyterfenadine, Terfenadine alcohol, 1-Piperidinebutanol, alpha-(4-(2-hydroxy-1,1-dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-, alpha-(4-(2-Hydroxy-1,1-dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol, .ALPHA.-(4-(2-HYDROXY-1,1-DIMETHYLETHYL)PHENYL)-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINEBUTANOL

CAS: 76815-56-0
Molecular Formula C32H41NO3
Molecular Weight 487.31 g/mol
LogP 5.4182
Topological Polar Surface Area 63.93 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 10
Exact Mass 487.30865
Heavy Atoms 36
Complexity 1018.07446

Chemical Identifiers

CAS Number 76815-56-0
SMILES CC(C)(CO)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O

Product Overview

Hydroxyterfenadine (CAS 76815-56-0), with molecular formula C32H41NO3 and molecular weight 487.31 g/mol. IUPAC: 4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]-1-[4-(1-hydroxy-2-methylpropan-2-yl)phenyl]butan-1-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Hydroxyterfenadine

XLogP
5.4182
TPSA (Topological Polar Surface Area)
63.93
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
10
Heavy Atoms
36
Complexity
1018.07446
Exact Mass
487.30865
Monoisotopic Mass
487.30865
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Hydroxyterfenadine

The XLogP value of 5.4182 indicates that Hydroxyterfenadine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.93 Ų falls within the moderate polarity range, balancing permeability and solubility for Hydroxyterfenadine. Following Lipinski's Rule of Five, Hydroxyterfenadine has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Hydroxyterfenadine?

The CAS number of Hydroxyterfenadine is 76815-56-0.

What is the molecular formula of Hydroxyterfenadine?

The molecular formula of Hydroxyterfenadine is C32H41NO3.

What is the molecular weight of Hydroxyterfenadine?

The molecular weight of Hydroxyterfenadine is 487.31 g/mol.

Where can I buy Hydroxyterfenadine?

You can request a quote for Hydroxyterfenadine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Hydroxyterfenadine?

Yes, KEHONG BIO provides custom synthesis services for Hydroxyterfenadine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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