alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride
TL;DR: alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride (CAS 768-35-4) is a chemical compound with molecular formula C10H8ClF3O2 and molecular weight 252.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
Also Known As: acetohexamide, MTPA chloride, 3,3,3-Trifluoro-2-methoxy-2-phenylpropanoyl chloride, Mosher's acid chloride, MTPA-C1
| Molecular Formula | C10H8ClF3O2 |
|---|---|
| Molecular Weight | 252.02 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 26.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 252.0165 |
| Heavy Atoms | 16 |
| Complexity | 261.0 |
Chemical Identifiers
| CAS Number | 768-35-4 |
|---|---|
| SMILES | COC(C1=CC=CC=C1)(C(=O)Cl)C(F)(F)F |
| InChIKey | PAORVUMOXXAMPL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride (CAS 768-35-4), with molecular formula C10H8ClF3O2 and molecular weight 252.02 g/mol. IUPAC: 3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride.
Chemical Property Profile of alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride
Property Insights of alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride
The XLogP value of 3.3 indicates that alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.3 Ų, alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride?
The CAS number of alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride is 768-35-4.
What is the molecular formula of alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride?
The molecular formula of alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride is C10H8ClF3O2.
What is the molecular weight of alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride?
The molecular weight of alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride is 252.02 g/mol.
Where can I buy alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride?
You can request a quote for alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride?
Yes, KEHONG BIO provides custom synthesis services for alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.