Thyrotropin releasing hormone diazomethyl ketone
TL;DR: Thyrotropin releasing hormone diazomethyl ketone (CAS 76760-06-0) is a chemical compound with molecular formula C17H21N7O4 and molecular weight 387.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-[(2S)-2-(2-diazoacetyl)pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Trh-dmk, Thyrotropin releasing hormone diazomethyl ketone, (Z)-2-diazonio-1-[(2S)-1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidin-2-yl]ethenolate, 2-Pyrrolidinecarboxamide, N-(2-(2-(diazoacetyl)-1-pyrrolidinyl)-1-(1H-imidazol-4-ylmethyl)-2-oxoethyl)-5-oxo-, (2S-(2R*(R*(R*))))-, (Z)-2-diazonio-1-[(2S)-1-[(2S)-3-(3H-imidazol-4-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidin-2-yl]ethenolate
| Molecular Formula | C17H21N7O4 |
|---|---|
| Molecular Weight | 387.17 g/mol |
| LogP | -1.6 |
| Topological Polar Surface Area | 126.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 387.1655 |
| Heavy Atoms | 28 |
| Complexity | 706.0 |
Chemical Identifiers
| CAS Number | 76760-06-0 |
|---|---|
| SMILES | C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)C=[N+]=[N-] |
| InChIKey | DOAVTKIPWOTKSR-AVGNSLFASA-N |
Product Overview
Thyrotropin releasing hormone diazomethyl ketone (CAS 76760-06-0), with molecular formula C17H21N7O4 and molecular weight 387.17 g/mol. IUPAC: (2S)-N-[(2S)-1-[(2S)-2-(2-diazoacetyl)pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of Thyrotropin releasing hormone diazomethyl ketone
Property Insights of Thyrotropin releasing hormone diazomethyl ketone
The XLogP value of -1.6 indicates that Thyrotropin releasing hormone diazomethyl ketone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 126.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Thyrotropin releasing hormone diazomethyl ketone. Following Lipinski's Rule of Five, Thyrotropin releasing hormone diazomethyl ketone has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thyrotropin releasing hormone diazomethyl ketone?
The CAS number of Thyrotropin releasing hormone diazomethyl ketone is 76760-06-0.
What is the molecular formula of Thyrotropin releasing hormone diazomethyl ketone?
The molecular formula of Thyrotropin releasing hormone diazomethyl ketone is C17H21N7O4.
What is the molecular weight of Thyrotropin releasing hormone diazomethyl ketone?
The molecular weight of Thyrotropin releasing hormone diazomethyl ketone is 387.17 g/mol.
Where can I buy Thyrotropin releasing hormone diazomethyl ketone?
You can request a quote for Thyrotropin releasing hormone diazomethyl ketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thyrotropin releasing hormone diazomethyl ketone?
Yes, KEHONG BIO provides custom synthesis services for Thyrotropin releasing hormone diazomethyl ketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.