22-Hydroxy-25-fluorocholesterol
TL;DR: 22-Hydroxy-25-fluorocholesterol (CAS 76752-41-5) is a chemical compound with molecular formula C27H45FO2 and molecular weight 420.34 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S,8S,9S,10R,13S,14S,17R)-17-[(2S)-6-fluoro-3-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Also Known As: 22-Hydroxy-25-fluorocholesterol, SC 32561, 25-Fluorocholest-5-ene-3,22-diol, 25-Fluorocholest-5-ene-3beta,22-diol, Cholest-5-ene-3,22-diol, 25-fluoro-, (3beta)-
| Molecular Formula | C27H45FO2 |
|---|---|
| Molecular Weight | 420.34 g/mol |
| LogP | 6.6 |
| Topological Polar Surface Area | 40.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 420.34036 |
| Heavy Atoms | 30 |
| Complexity | 672.0 |
Chemical Identifiers
| CAS Number | 76752-41-5 |
|---|---|
| SMILES | C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C(CCC(C)(C)F)O |
| InChIKey | HAAJKVUMSLGIDT-LOUMIQLRSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
22-Hydroxy-25-fluorocholesterol (CAS 76752-41-5), with molecular formula C27H45FO2 and molecular weight 420.34 g/mol. IUPAC: (3S,8S,9S,10R,13S,14S,17R)-17-[(2S)-6-fluoro-3-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol.
Chemical Property Profile of 22-Hydroxy-25-fluorocholesterol
Property Insights of 22-Hydroxy-25-fluorocholesterol
The XLogP value of 6.6 indicates that 22-Hydroxy-25-fluorocholesterol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.5 Ų, 22-Hydroxy-25-fluorocholesterol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 22-Hydroxy-25-fluorocholesterol has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 22-Hydroxy-25-fluorocholesterol?
The CAS number of 22-Hydroxy-25-fluorocholesterol is 76752-41-5.
What is the molecular formula of 22-Hydroxy-25-fluorocholesterol?
The molecular formula of 22-Hydroxy-25-fluorocholesterol is C27H45FO2.
What is the molecular weight of 22-Hydroxy-25-fluorocholesterol?
The molecular weight of 22-Hydroxy-25-fluorocholesterol is 420.34 g/mol.
Where can I buy 22-Hydroxy-25-fluorocholesterol?
You can request a quote for 22-Hydroxy-25-fluorocholesterol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 22-Hydroxy-25-fluorocholesterol?
Yes, KEHONG BIO provides custom synthesis services for 22-Hydroxy-25-fluorocholesterol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.