EP 459
TL;DR: EP 459 (CAS 76739-51-0) is a chemical compound with molecular formula C14H25N3O5 and molecular weight 315.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
EP 459
(2S,3S)-3-[[(2S)-1-(4-aminobutylamino)-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
Also Known As: E 64a, E-64a, (2S,3S)-3-[[(2S)-1-(4-aminobutylamino)-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid, Oxiranecarboxylic acid, 3-(((1-(((4-aminobutyl)amino)carbonyl)-3-methylbutyl)amino)carbonyl)-, (2S-(2alpha,3beta(R*)))-, (2S)-3beta-[[[(S)-1-[[(4-Aminobutyl)amino]carbonyl]-3-methylbutyl]amino]carbonyl]oxirane-2alpha-carboxylic acid
| Molecular Formula | C14H25N3O5 |
|---|---|
| Molecular Weight | 315.18 g/mol |
| LogP | -2.6 |
| Topological Polar Surface Area | 134.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 10 |
| Exact Mass | 315.1794 |
| Heavy Atoms | 22 |
| Complexity | 413.0 |
Chemical Identifiers
| CAS Number | 76739-51-0 |
|---|---|
| SMILES | CC(C)C[C@@H](C(=O)NCCCCN)NC(=O)[C@@H]1[C@H](O1)C(=O)O |
| InChIKey | AVTVMICMSRMLMA-DCAQKATOSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
EP 459 (CAS 76739-51-0), with molecular formula C14H25N3O5 and molecular weight 315.18 g/mol. IUPAC: (2S,3S)-3-[[(2S)-1-(4-aminobutylamino)-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid.
Chemical Property Profile of EP 459
Property Insights of EP 459
The XLogP value of -2.6 indicates that EP 459 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 134.0 Ų falls within the moderate polarity range, balancing permeability and solubility for EP 459. Following Lipinski's Rule of Five, EP 459 has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of EP 459?
The CAS number of EP 459 is 76739-51-0.
What is the molecular formula of EP 459?
The molecular formula of EP 459 is C14H25N3O5.
What is the molecular weight of EP 459?
The molecular weight of EP 459 is 315.18 g/mol.
Where can I buy EP 459?
You can request a quote for EP 459 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for EP 459?
Yes, KEHONG BIO provides custom synthesis services for EP 459 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.