![6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine structure](/static/products/766/766497-25-0.png)
6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine
TL;DR: 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine (CAS 766497-25-0) is a chemical compound with molecular formula C25H31N3O4Si and molecular weight 465.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6,7-bis(2-methoxyethoxy)-N-[3-(2-trimethylsilylethynyl)phenyl]quinazolin-4-amine
Also Known As: 6,7-bis(2-methoxyethoxy)-N-[3-(2-trimethylsilylethynyl)phenyl]quinazolin-4-amine, 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine, 4-Quinazolinamine, 6,7-bis(2-methoxyethoxy)-N-[3-[2-(trimethylsilyl)ethynyl]phenyl]-; 4-Quinazolinamine, 6,7-bis(2-methoxyethoxy)-N-[3-[(trimethylsilyl)ethynyl]phenyl]- (9CI); Erlotinib trimethylsilyl; 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine; 6,7-Bis(2-methoxyethoxy)-4-[[3-(trimethylsilylethynyl)phenyl]amino]quinazoline; Trimethylsilylethynylerlotinib
| Molecular Formula | C25H31N3O4Si |
|---|---|
| Molecular Weight | 465.21 g/mol |
| LogP | 4.6527 |
| Topological Polar Surface Area | 74.73 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 10 |
| Exact Mass | 465.20837 |
| Heavy Atoms | 33 |
| Complexity | 1135.9258 |
Chemical Identifiers
| CAS Number | 766497-25-0 |
|---|---|
| SMILES | COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C[Si](C)(C)C)OCCOC |
Product Overview
6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine (CAS 766497-25-0), with molecular formula C25H31N3O4Si and molecular weight 465.21 g/mol. IUPAC: 6,7-bis(2-methoxyethoxy)-N-[3-(2-trimethylsilylethynyl)phenyl]quinazolin-4-amine.
Chemical Property Profile of 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine
Property Insights of 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine
The XLogP value of 4.6527 indicates that 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 74.73 Ų falls within the moderate polarity range, balancing permeability and solubility for 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine. Following Lipinski's Rule of Five, 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine?
The CAS number of 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine is 766497-25-0.
What is the molecular formula of 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine?
The molecular formula of 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine is C25H31N3O4Si.
What is the molecular weight of 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine?
The molecular weight of 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine is 465.21 g/mol.
Where can I buy 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine?
You can request a quote for 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine?
Yes, KEHONG BIO provides custom synthesis services for 6,7-Bis(2-methoxyethoxy)-N-[3-(trimethylsilylethynyl)phenyl]-4-quinazolinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.