16-Methylene estradiol
TL;DR: 16-Methylene estradiol (CAS 7627-87-4) is a chemical compound with molecular formula C19H24O2 and molecular weight 284.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,9S,13S,14S,17S)-13-methyl-16-methylidene-7,8,9,11,12,14,15,17-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Also Known As: 16-Methylene estradiol, 16-Methylene-estradiol, 16-methyleneestradiol, 16-methylenestradiol, 16-Methylene-17beta-estradiol
| Molecular Formula | C19H24O2 |
|---|---|
| Molecular Weight | 284.18 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 40.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 284.17764 |
| Heavy Atoms | 21 |
| Complexity | 445.0 |
Chemical Identifiers
| CAS Number | 7627-87-4 |
|---|---|
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CC(=C)[C@@H]2O)CCC4=C3C=CC(=C4)O |
| InChIKey | DJEKMVJLSAUQAO-GFEQUFNTSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
16-Methylene estradiol (CAS 7627-87-4), with molecular formula C19H24O2 and molecular weight 284.18 g/mol. IUPAC: (8R,9S,13S,14S,17S)-13-methyl-16-methylidene-7,8,9,11,12,14,15,17-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol.
Chemical Property Profile of 16-Methylene estradiol
Property Insights of 16-Methylene estradiol
The XLogP value of 3.7 indicates that 16-Methylene estradiol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.5 Ų, 16-Methylene estradiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 16-Methylene estradiol has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 16-Methylene estradiol?
The CAS number of 16-Methylene estradiol is 7627-87-4.
What is the molecular formula of 16-Methylene estradiol?
The molecular formula of 16-Methylene estradiol is C19H24O2.
What is the molecular weight of 16-Methylene estradiol?
The molecular weight of 16-Methylene estradiol is 284.18 g/mol.
Where can I buy 16-Methylene estradiol?
You can request a quote for 16-Methylene estradiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 16-Methylene estradiol?
Yes, KEHONG BIO provides custom synthesis services for 16-Methylene estradiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.