10-Benzylamino-10-demethoxycolchicine
TL;DR: 10-Benzylamino-10-demethoxycolchicine (CAS 76129-15-2) is a chemical compound with molecular formula C28H30N2O5 and molecular weight 474.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-10-(benzylamino)-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: 10-Benzylamino-10-demethoxycolchicine, Colchicine, 10-(benzylamino)-10-demethoxy-, 10-(Benzylamino)-10-demethoxycolchicine, 4-14-00-00924 (Beilstein Handbook Reference), Acetamide, N-(5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxo-10-((phenylmethyl)amino)benzo(a)heptalen-7-yl)-, (S)-
| Molecular Formula | C28H30N2O5 |
|---|---|
| Molecular Weight | 474.22 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 85.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 474.21548 |
| Heavy Atoms | 35 |
| Complexity | 873.0 |
Chemical Identifiers
| CAS Number | 76129-15-2 |
|---|---|
| SMILES | CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)NCC4=CC=CC=C4)OC)OC)OC |
| InChIKey | PDIUZPBNLUNFFJ-QFIPXVFZSA-N |
Product Overview
10-Benzylamino-10-demethoxycolchicine (CAS 76129-15-2), with molecular formula C28H30N2O5 and molecular weight 474.22 g/mol. IUPAC: N-[(7S)-10-(benzylamino)-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of 10-Benzylamino-10-demethoxycolchicine
Property Insights of 10-Benzylamino-10-demethoxycolchicine
The XLogP value of 3.6 indicates that 10-Benzylamino-10-demethoxycolchicine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 10-Benzylamino-10-demethoxycolchicine. Following Lipinski's Rule of Five, 10-Benzylamino-10-demethoxycolchicine has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10-Benzylamino-10-demethoxycolchicine?
The CAS number of 10-Benzylamino-10-demethoxycolchicine is 76129-15-2.
What is the molecular formula of 10-Benzylamino-10-demethoxycolchicine?
The molecular formula of 10-Benzylamino-10-demethoxycolchicine is C28H30N2O5.
What is the molecular weight of 10-Benzylamino-10-demethoxycolchicine?
The molecular weight of 10-Benzylamino-10-demethoxycolchicine is 474.22 g/mol.
Where can I buy 10-Benzylamino-10-demethoxycolchicine?
You can request a quote for 10-Benzylamino-10-demethoxycolchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10-Benzylamino-10-demethoxycolchicine?
Yes, KEHONG BIO provides custom synthesis services for 10-Benzylamino-10-demethoxycolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.