(+)-Nicardipine
TL;DR: (+)-Nicardipine (CAS 76093-35-1) is a chemical compound with molecular formula C26H29N3O6 and molecular weight 479.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: (R)-Nicardipine, nicardipine, (+)-Nicardipine, Nicardipine, (R)-, (-)-Nicardipine
| Molecular Formula | C26H29N3O6 |
|---|---|
| Molecular Weight | 479.21 g/mol |
| LogP | 3.6778 |
| Topological Polar Surface Area | 111.01 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 9 |
| Exact Mass | 479.20563 |
| Heavy Atoms | 35 |
| Complexity | 1172.6194 |
Chemical Identifiers
| CAS Number | 76093-35-1 |
|---|---|
| SMILES | CC1=C([C@H](C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC |
Product Overview
(+)-Nicardipine (CAS 76093-35-1), with molecular formula C26H29N3O6 and molecular weight 479.21 g/mol. IUPAC: 5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of (+)-Nicardipine
Property Insights of (+)-Nicardipine
The XLogP value of 3.6778 indicates that (+)-Nicardipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 111.01 Ų falls within the moderate polarity range, balancing permeability and solubility for (+)-Nicardipine. Following Lipinski's Rule of Five, (+)-Nicardipine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (+)-Nicardipine?
The CAS number of (+)-Nicardipine is 76093-35-1.
What is the molecular formula of (+)-Nicardipine?
The molecular formula of (+)-Nicardipine is C26H29N3O6.
What is the molecular weight of (+)-Nicardipine?
The molecular weight of (+)-Nicardipine is 479.21 g/mol.
Where can I buy (+)-Nicardipine?
You can request a quote for (+)-Nicardipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (+)-Nicardipine?
Yes, KEHONG BIO provides custom synthesis services for (+)-Nicardipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.