3'-O-(4,4'-Dimethoxytrityl)-thymidine
TL;DR: 3'-O-(4,4'-Dimethoxytrityl)-thymidine (CAS 76054-81-4) is a chemical compound with molecular formula C31H32N2O7 and molecular weight 544.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5R)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: 3'-O-DMT-thymidine, 3'-O-dimethoxytritylthymidine, 3'-O-(4,4'-dimethoxytrityl)thymidine, 3'-O-(4,4'-dimethoxytrityl)-thymidine, Thymidine,3'-O-[bis(4-methoxyphenyl)phenylmethyl]-
| Molecular Formula | C31H32N2O7 |
|---|---|
| Molecular Weight | 544.22 g/mol |
| LogP | 3.51932 |
| Topological Polar Surface Area | 112.01 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 9 |
| Exact Mass | 544.22095 |
| Heavy Atoms | 40 |
| Complexity | 1498.6178 |
Chemical Identifiers
| CAS Number | 76054-81-4 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)OC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC |
Product Overview
3'-O-(4,4'-Dimethoxytrityl)-thymidine (CAS 76054-81-4), with molecular formula C31H32N2O7 and molecular weight 544.22 g/mol. IUPAC: 1-[(2R,4S,5R)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 3'-O-(4,4'-Dimethoxytrityl)-thymidine
Property Insights of 3'-O-(4,4'-Dimethoxytrityl)-thymidine
The XLogP value of 3.51932 indicates that 3'-O-(4,4'-Dimethoxytrityl)-thymidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 112.01 Ų falls within the moderate polarity range, balancing permeability and solubility for 3'-O-(4,4'-Dimethoxytrityl)-thymidine. Following Lipinski's Rule of Five, 3'-O-(4,4'-Dimethoxytrityl)-thymidine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-O-(4,4'-Dimethoxytrityl)-thymidine?
The CAS number of 3'-O-(4,4'-Dimethoxytrityl)-thymidine is 76054-81-4.
What is the molecular formula of 3'-O-(4,4'-Dimethoxytrityl)-thymidine?
The molecular formula of 3'-O-(4,4'-Dimethoxytrityl)-thymidine is C31H32N2O7.
What is the molecular weight of 3'-O-(4,4'-Dimethoxytrityl)-thymidine?
The molecular weight of 3'-O-(4,4'-Dimethoxytrityl)-thymidine is 544.22 g/mol.
Where can I buy 3'-O-(4,4'-Dimethoxytrityl)-thymidine?
You can request a quote for 3'-O-(4,4'-Dimethoxytrityl)-thymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-O-(4,4'-Dimethoxytrityl)-thymidine?
Yes, KEHONG BIO provides custom synthesis services for 3'-O-(4,4'-Dimethoxytrityl)-thymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.