NSC 151998 (Sweeney)
TL;DR: NSC 151998 (Sweeney) (CAS 76004-86-9) is a chemical compound with molecular formula C21H22Cl3N5 and molecular weight 449.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-2-N-(3,4-dichlorophenyl)-4-N-[2-(1-methylpyrrolidin-2-yl)ethyl]quinazoline-2,4-diamine
Also Known As: NSC 151998 (Sweeney), 6-Chloro-N2-(3,4-dichlorophenyl)-N4-(2-(1-methyl-2-pyrrolidinyl)ethyl)-2,4-quinazolinediamine, 6-Chloro-N2-(3,4-dichlorophenyl)-N4-(2-(1-methylpyrrolidin-2-yl)ethyl)quinazoline-2,4-diamine, 6-chloro-N2-(3,4-dichlorophenyl)-N4-[2-(1-methylpyrrolidin-2-yl)ethyl]quinazoline-2,4-diamine, 6-chloro-2-N-(3,4-dichlorophenyl)-4-N-[2-(1-methylpyrrolidin-2-yl)ethyl]quinazoline-2,4-diamine
| Molecular Formula | C21H22Cl3N5 |
|---|---|
| Molecular Weight | 449.09 g/mol |
| LogP | 6.6 |
| Topological Polar Surface Area | 53.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 449.0941 |
| Heavy Atoms | 29 |
| Complexity | 527.0 |
Chemical Identifiers
| CAS Number | 76004-86-9 |
|---|---|
| SMILES | CN1CCCC1CCNC2=NC(=NC3=C2C=C(C=C3)Cl)NC4=CC(=C(C=C4)Cl)Cl |
| InChIKey | NXVAKNZKQLCDTC-UHFFFAOYSA-N |
Product Overview
NSC 151998 (Sweeney) (CAS 76004-86-9), with molecular formula C21H22Cl3N5 and molecular weight 449.09 g/mol. IUPAC: 6-chloro-2-N-(3,4-dichlorophenyl)-4-N-[2-(1-methylpyrrolidin-2-yl)ethyl]quinazoline-2,4-diamine.
Chemical Property Profile of NSC 151998 (Sweeney)
Property Insights of NSC 151998 (Sweeney)
The XLogP value of 6.6 indicates that NSC 151998 (Sweeney) is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.1 Ų, NSC 151998 (Sweeney) exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, NSC 151998 (Sweeney) has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of NSC 151998 (Sweeney)?
The CAS number of NSC 151998 (Sweeney) is 76004-86-9.
What is the molecular formula of NSC 151998 (Sweeney)?
The molecular formula of NSC 151998 (Sweeney) is C21H22Cl3N5.
What is the molecular weight of NSC 151998 (Sweeney)?
The molecular weight of NSC 151998 (Sweeney) is 449.09 g/mol.
Where can I buy NSC 151998 (Sweeney)?
You can request a quote for NSC 151998 (Sweeney) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for NSC 151998 (Sweeney)?
Yes, KEHONG BIO provides custom synthesis services for NSC 151998 (Sweeney) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.