Betamethasone 21-propionate
TL;DR: Betamethasone 21-propionate (CAS 75883-07-7) is a chemical compound with molecular formula C25H33FO6 and molecular weight 448.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
Also Known As: Betamethasone 21-Propionate, Betamethasone-21-Propionate, Clobetasol Propionate EP Impurity K, MSK162016-100A, BETAMETHASONE DIPROPIONATE IMPURITY C
| Molecular Formula | C25H33FO6 |
|---|---|
| Molecular Weight | 448.23 g/mol |
| LogP | 2.8566 |
| Topological Polar Surface Area | 100.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 448.2261 |
| Heavy Atoms | 32 |
| Complexity | 925.39294 |
Chemical Identifiers
| CAS Number | 75883-07-7 |
|---|---|
| SMILES | CCC(=O)OCC(=O)[C@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)O |
Product Overview
Betamethasone 21-propionate (CAS 75883-07-7), with molecular formula C25H33FO6 and molecular weight 448.23 g/mol. IUPAC: [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate.
Chemical Property Profile of Betamethasone 21-propionate
Property Insights of Betamethasone 21-propionate
The XLogP value of 2.8566 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Betamethasone 21-propionate. The TPSA of 100.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Betamethasone 21-propionate. Following Lipinski's Rule of Five, Betamethasone 21-propionate has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Betamethasone 21-propionate?
The CAS number of Betamethasone 21-propionate is 75883-07-7.
What is the molecular formula of Betamethasone 21-propionate?
The molecular formula of Betamethasone 21-propionate is C25H33FO6.
What is the molecular weight of Betamethasone 21-propionate?
The molecular weight of Betamethasone 21-propionate is 448.23 g/mol.
Where can I buy Betamethasone 21-propionate?
You can request a quote for Betamethasone 21-propionate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Betamethasone 21-propionate?
Yes, KEHONG BIO provides custom synthesis services for Betamethasone 21-propionate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.