Colistin heptapeptide
TL;DR: Colistin heptapeptide (CAS 75748-25-3) is a chemical compound with molecular formula C32H61N11O8 and molecular weight 727.47 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
21-amino-6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-1,4,7,10,13,16,19-heptazacyclotricosane-2,5,8,11,14,17,20-heptone
Also Known As: Colistin heptapeptide, 21-amino-6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-1,4,7,10,13,16,19-heptazacyclotricosane-2,5,8,11,14,17,20-heptone, Polymyxin E1,1-de[N2-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoicacid]-2-de-L-threonine-3-de(L-2,4-diaminobutanoic acid)- (9CI), 21-Amino-6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-1,4,7,10,13,16,19-heptaazacyclotricosa-1,4,7,10,13,16,19-heptaene-2,5,8,11,14,17,20-heptol, Polymyxin E1, 1-de(N2-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid)-2-de-L-threonine-3-de(L-2,4-diaminobutanoic acid)-, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))-
| Molecular Formula | C32H61N11O8 |
|---|---|
| Molecular Weight | 727.47 g/mol |
| LogP | -3.0 |
| Topological Polar Surface Area | 328.0 Ų |
| Hydrogen Bond Donors | 12 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 11 |
| Exact Mass | 727.47046 |
| Heavy Atoms | 51 |
| Complexity | 1190.0 |
Chemical Identifiers
| CAS Number | 75748-25-3 |
|---|---|
| SMILES | CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCCC(C(=O)NC(C(=O)N1)CCN)N)C(C)O)CCN)CCN)CC(C)C |
| InChIKey | HCSATRDQWBMHRF-UHFFFAOYSA-N |
Product Overview
Colistin heptapeptide (CAS 75748-25-3), with molecular formula C32H61N11O8 and molecular weight 727.47 g/mol. IUPAC: 21-amino-6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-1,4,7,10,13,16,19-heptazacyclotricosane-2,5,8,11,14,17,20-heptone.
Chemical Property Profile of Colistin heptapeptide
Property Insights of Colistin heptapeptide
The XLogP value of -3.0 indicates that Colistin heptapeptide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 328.0 Ų indicates high polarity, suggesting Colistin heptapeptide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Colistin heptapeptide has 12 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colistin heptapeptide?
The CAS number of Colistin heptapeptide is 75748-25-3.
What is the molecular formula of Colistin heptapeptide?
The molecular formula of Colistin heptapeptide is C32H61N11O8.
What is the molecular weight of Colistin heptapeptide?
The molecular weight of Colistin heptapeptide is 727.47 g/mol.
Where can I buy Colistin heptapeptide?
You can request a quote for Colistin heptapeptide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colistin heptapeptide?
Yes, KEHONG BIO provides custom synthesis services for Colistin heptapeptide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.