![4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine structure](/static/products/7571/757178-55-5.webp)
4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine
TL;DR: 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine (CAS 757178-55-5) is a chemical compound with molecular formula C11H8F4N2O2S and molecular weight 308.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[2,4-bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine
Also Known As: 4-[2,4-bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine, 4-(2,4-Bis-difluoromethoxy-phenyl)-thiazol-2-ylamine, 4-[2,4-bis(difluoromethoxy)phenyl]thiazol-2-amine, 4-[2,4-bis(difluoromethoxy)phenyl]-1,3-thiazol-2-ylamine, 4-[2,4-bis(difluoromethoxy)phenyl]-1,3-thiazole-2-ylamine
| Molecular Formula | C11H8F4N2O2S |
|---|---|
| Molecular Weight | 308.02 g/mol |
| LogP | 3.5951 |
| Topological Polar Surface Area | 57.37 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 308.02426 |
| Heavy Atoms | 20 |
| Complexity | 591.5521 |
Chemical Identifiers
| CAS Number | 757178-55-5 |
|---|---|
| SMILES | C1=CC(=C(C=C1OC(F)F)OC(F)F)C2=CSC(=N2)N |
Product Overview
4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine (CAS 757178-55-5), with molecular formula C11H8F4N2O2S and molecular weight 308.02 g/mol. IUPAC: 4-[2,4-bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine.
Chemical Property Profile of 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine
Property Insights of 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine
The XLogP value of 3.5951 indicates that 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.37 Ų, 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine?
The CAS number of 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine is 757178-55-5.
What is the molecular formula of 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine?
The molecular formula of 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine is C11H8F4N2O2S.
What is the molecular weight of 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine?
The molecular weight of 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine is 308.02 g/mol.
Where can I buy 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine?
You can request a quote for 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-[2,4-Bis(difluoromethoxy)phenyl]-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.