11-trans-LTE4
TL;DR: 11-trans-LTE4 (CAS 75715-88-7) is a chemical compound with molecular formula C23H37NO5S and molecular weight 439.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5S,6R,7E,9E,11E,14Z)-6-[(2R)-2-amino-2-carboxyethyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid
Also Known As: 11-trans Leukotriene E4, 11-trans-LTE4, thioglycolicacid, leukotriene E4, 11-trans-Leukotriene E4
| Molecular Formula | C23H37NO5S |
|---|---|
| Molecular Weight | 439.24 g/mol |
| LogP | 4.3111 |
| Topological Polar Surface Area | 120.85 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 18 |
| Exact Mass | 439.23926 |
| Heavy Atoms | 30 |
| Complexity | 586.1425 |
Chemical Identifiers
| CAS Number | 75715-88-7 |
|---|---|
| SMILES | CCCCC/C=C\C/C=C/C=C/C=C/[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)O)N |
Product Overview
11-trans-LTE4 (CAS 75715-88-7), with molecular formula C23H37NO5S and molecular weight 439.24 g/mol. IUPAC: (5S,6R,7E,9E,11E,14Z)-6-[(2R)-2-amino-2-carboxyethyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid.
Chemical Property Profile of 11-trans-LTE4
Property Insights of 11-trans-LTE4
The XLogP value of 4.3111 indicates that 11-trans-LTE4 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 120.85 Ų falls within the moderate polarity range, balancing permeability and solubility for 11-trans-LTE4. Following Lipinski's Rule of Five, 11-trans-LTE4 has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 11-trans-LTE4?
The CAS number of 11-trans-LTE4 is 75715-88-7.
What is the molecular formula of 11-trans-LTE4?
The molecular formula of 11-trans-LTE4 is C23H37NO5S.
What is the molecular weight of 11-trans-LTE4?
The molecular weight of 11-trans-LTE4 is 439.24 g/mol.
Where can I buy 11-trans-LTE4?
You can request a quote for 11-trans-LTE4 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 11-trans-LTE4?
Yes, KEHONG BIO provides custom synthesis services for 11-trans-LTE4 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.