Hoe 402
TL;DR: Hoe 402 (CAS 75690-41-4) is a chemical compound with molecular formula C17H18ClF3N6O2 and molecular weight 430.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-2-(4,4-dimethyl-2-oxoimidazolidin-1-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide;hydrochloride
Also Known As: Hoe 402, 5-Pyrimidinecarboxamide, 4-amino-2-(4,4-dimethyl-2-oxo-1-imidazolidinyl)-N-(3-(trifluoromethyl)phenyl)-, monohydrochloride, 4-Amino-2-(4,4-dimethyl-2-oxo-1-imidazolidinyl)pyrimidine-5-N-(trifluoromethylphenyl)carboxamide, 4-amino-2-(4,4-dimethyl-2-oxoimidazolidin-1-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide;hydrochloride, 4-Amino-2-(4,4-dimethyl-2-oxo-1-imidazolidinyl)-pyrimidin-5-carbonsaure-N-(3-trifluoromethyl-phenyl)-amid-monohydrochlorid
| Molecular Formula | C17H18ClF3N6O2 |
|---|---|
| Molecular Weight | 430.11 g/mol |
| LogP | 3.0599 |
| Topological Polar Surface Area | 113.24 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 430.1132 |
| Heavy Atoms | 29 |
| Complexity | 951.00574 |
Chemical Identifiers
| CAS Number | 75690-41-4 |
|---|---|
| SMILES | CC1(CN(C(=O)N1)C2=NC=C(C(=N2)N)C(=O)NC3=CC=CC(=C3)C(F)(F)F)C.Cl |
Product Overview
Hoe 402 (CAS 75690-41-4), with molecular formula C17H18ClF3N6O2 and molecular weight 430.11 g/mol. IUPAC: 4-amino-2-(4,4-dimethyl-2-oxoimidazolidin-1-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide;hydrochloride.
Chemical Property Profile of Hoe 402
Property Insights of Hoe 402
The XLogP value of 3.0599 indicates that Hoe 402 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 113.24 Ų falls within the moderate polarity range, balancing permeability and solubility for Hoe 402. Following Lipinski's Rule of Five, Hoe 402 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Hoe 402?
The CAS number of Hoe 402 is 75690-41-4.
What is the molecular formula of Hoe 402?
The molecular formula of Hoe 402 is C17H18ClF3N6O2.
What is the molecular weight of Hoe 402?
The molecular weight of Hoe 402 is 430.11 g/mol.
Where can I buy Hoe 402?
You can request a quote for Hoe 402 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Hoe 402?
Yes, KEHONG BIO provides custom synthesis services for Hoe 402 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.