![3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide structure](/static/products/7568/756856-75-4.webp)
3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide
TL;DR: 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide (CAS 756856-75-4) is a chemical compound with molecular formula C15H9F4N3O3S and molecular weight 387.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide
Also Known As: (Z)-3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide, 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide
| Molecular Formula | C15H9F4N3O3S |
|---|---|
| Molecular Weight | 387.03 g/mol |
| LogP | 3.89158 |
| Topological Polar Surface Area | 84.24 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 387.03006 |
| Heavy Atoms | 26 |
| Complexity | 835.1573 |
Chemical Identifiers
| CAS Number | 756856-75-4 |
|---|---|
| SMILES | C1=CC(=C(C=C1OC(F)F)OC(F)F)/C=C(/C#N)\C(=O)NC2=NC=CS2 |
Product Overview
3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide (CAS 756856-75-4), with molecular formula C15H9F4N3O3S and molecular weight 387.03 g/mol. IUPAC: (Z)-3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide.
Chemical Property Profile of 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide
Property Insights of 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide
The XLogP value of 3.89158 indicates that 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.24 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide. Following Lipinski's Rule of Five, 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide?
The CAS number of 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide is 756856-75-4.
What is the molecular formula of 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide?
The molecular formula of 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide is C15H9F4N3O3S.
What is the molecular weight of 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide?
The molecular weight of 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide is 387.03 g/mol.
Where can I buy 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide?
You can request a quote for 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for 3-[2,4-bis(difluoromethoxy)phenyl]-2-cyano-N-(1,3-thiazol-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.