Cyclo(-D-His-Pro) structure

Cyclo(-D-His-Pro)

TL;DR: Cyclo(-D-His-Pro) (CAS 75685-88-0) is a chemical compound with molecular formula C11H14N4O2 and molecular weight 234.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3R,8aS)-3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Also Known As: Cyclo(-D-His-Pro), Cyclo(D-His-Pro), cyclo(D-histidyl-L-proline), NCI60_006749, (3R,8aS)-3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

CAS: 75685-88-0
Molecular Formula C11H14N4O2
Molecular Weight 234.11 g/mol
LogP -0.4
Topological Polar Surface Area 78.1 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 234.11168
Heavy Atoms 17
Complexity 346.0

Chemical Identifiers

CAS Number 75685-88-0
SMILES C1C[C@H]2C(=O)N[C@@H](C(=O)N2C1)CC3=CN=CN3
InChIKey NAKUGCPAQTUSBE-BDAKNGLRSA-N

Product Overview

Cyclo(-D-His-Pro) (CAS 75685-88-0), with molecular formula C11H14N4O2 and molecular weight 234.11 g/mol. IUPAC: (3R,8aS)-3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Cyclo(-D-His-Pro)

XLogP
-0.4
TPSA (Topological Polar Surface Area)
78.1
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
17
Complexity
346.0
Exact Mass
234.11168
Monoisotopic Mass
234.11168
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Cyclo(-D-His-Pro)

The XLogP value of -0.4 indicates that Cyclo(-D-His-Pro) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 78.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Cyclo(-D-His-Pro). Following Lipinski's Rule of Five, Cyclo(-D-His-Pro) has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Cyclo(-D-His-Pro)?

The CAS number of Cyclo(-D-His-Pro) is 75685-88-0.

What is the molecular formula of Cyclo(-D-His-Pro)?

The molecular formula of Cyclo(-D-His-Pro) is C11H14N4O2.

What is the molecular weight of Cyclo(-D-His-Pro)?

The molecular weight of Cyclo(-D-His-Pro) is 234.11 g/mol.

Where can I buy Cyclo(-D-His-Pro)?

You can request a quote for Cyclo(-D-His-Pro) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Cyclo(-D-His-Pro)?

Yes, KEHONG BIO provides custom synthesis services for Cyclo(-D-His-Pro) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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