Ribosyl-diphthamide structure

Ribosyl-diphthamide

TL;DR: Ribosyl-diphthamide (CAS 75652-53-8) is a chemical compound with molecular formula C18H31N5O7 and molecular weight 429.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-amino-3-[2-[4-amino-4-oxo-3-(trimethylazaniumyl)butyl]-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazol-4-yl]propanoate

Also Known As: Ribosyl-diphthamide, 2-amino-3-[2-[4-amino-4-oxo-3-(trimethylazaniumyl)butyl]-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazol-4-yl]propanoate, 1H-Imidazole-2-propanaminium, alpha-(aminocarbonyl)-4-(2-amino-2-carboxyethyl)-N,N,N-trimethyl-1-beta-D-ribofuranosyl-, hydroxide, inner salt, 4-(2-Amino-2-carboxylatoethyl)-2-[4-hydroxy-4-imino-3-(trimethylazaniumyl)butyl]-1-beta-D-ribofuranosyl-1H-imidazole, 4-(2-Amino-2-carboxylatoethyl)-2-[4-hydroxy-4-imino-3-(trimethylazaniumyl)butyl]-1-pentofuranosyl-1H-imidazole

CAS: 75652-53-8
Molecular Formula C18H31N5O7
Molecular Weight 429.22 g/mol
LogP -4.6
Topological Polar Surface Area 197.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 9
Rotatable Bonds 9
Exact Mass 429.22235
Heavy Atoms 30
Complexity 611.0

Chemical Identifiers

CAS Number 75652-53-8
SMILES C[N+](C)(C)C(CCC1=NC(=CN1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)CC(C(=O)[O-])N)C(=O)N
InChIKey ZBHYRBYADYEBBR-QJEBFMIZSA-N

Product Overview

Ribosyl-diphthamide (CAS 75652-53-8), with molecular formula C18H31N5O7 and molecular weight 429.22 g/mol. IUPAC: 2-amino-3-[2-[4-amino-4-oxo-3-(trimethylazaniumyl)butyl]-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazol-4-yl]propanoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Ribosyl-diphthamide

XLogP
-4.6
TPSA (Topological Polar Surface Area)
197.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
9
Rotatable Bonds
9
Heavy Atoms
30
Complexity
611.0
Exact Mass
429.22235
Monoisotopic Mass
429.22235
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ribosyl-diphthamide

The XLogP value of -4.6 indicates that Ribosyl-diphthamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 197.0 Ų indicates high polarity, suggesting Ribosyl-diphthamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Ribosyl-diphthamide has 5 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ribosyl-diphthamide?

The CAS number of Ribosyl-diphthamide is 75652-53-8.

What is the molecular formula of Ribosyl-diphthamide?

The molecular formula of Ribosyl-diphthamide is C18H31N5O7.

What is the molecular weight of Ribosyl-diphthamide?

The molecular weight of Ribosyl-diphthamide is 429.22 g/mol.

Where can I buy Ribosyl-diphthamide?

You can request a quote for Ribosyl-diphthamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ribosyl-diphthamide?

Yes, KEHONG BIO provides custom synthesis services for Ribosyl-diphthamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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