5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one
TL;DR: 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one (CAS 75643-42-4) is a chemical compound with molecular formula C18H12F2N2O2 and molecular weight 326.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one
Also Known As: 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one, 4-Acetyl-5,6-bis(4-fluorophenyl)pyridazin-3(2H)-one
| Molecular Formula | C18H12F2N2O2 |
|---|---|
| Molecular Weight | 326.09 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 58.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 326.08667 |
| Heavy Atoms | 24 |
| Complexity | 584.0 |
Chemical Identifiers
| CAS Number | 75643-42-4 |
|---|---|
| SMILES | CC(=O)C1=C(C(=NNC1=O)C2=CC=C(C=C2)F)C3=CC=C(C=C3)F |
| InChIKey | KHYPTVAMXRKHPB-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one (CAS 75643-42-4), with molecular formula C18H12F2N2O2 and molecular weight 326.09 g/mol. IUPAC: 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one.
Chemical Property Profile of 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one
Property Insights of 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one
The XLogP value of 3.0 indicates that 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.5 Ų, 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one?
The CAS number of 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one is 75643-42-4.
What is the molecular formula of 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one?
The molecular formula of 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one is C18H12F2N2O2.
What is the molecular weight of 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one?
The molecular weight of 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one is 326.09 g/mol.
Where can I buy 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one?
You can request a quote for 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one?
Yes, KEHONG BIO provides custom synthesis services for 5-acetyl-3,4-bis(4-fluorophenyl)-1H-pyridazin-6-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.