洛伐他汀
TL;DR: 洛伐他汀 (CAS 75330-75-5) is a chemical compound with molecular formula C24H36O5 and molecular weight 404.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
洛伐他汀
[8-[2-(4-hydroxy-6-oxooxan-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylbutanoate
Also Known As: lovastatin, Epilovastatin, mevinolin, Lovastin, Epi Lovastatin
| Molecular Formula | C24H36O5 |
|---|---|
| Molecular Weight | 404.26 g/mol |
| LogP | 4.3 |
| Topological Polar Surface Area | 72.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 404.2563 |
| Heavy Atoms | 29 |
| Complexity | 666.0 |
Chemical Identifiers
| CAS Number | 75330-75-5 |
|---|---|
| SMILES | CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C |
| InChIKey | PCZOHLXUXFIOCF-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
洛伐他汀 (CAS 75330-75-5), with molecular formula C24H36O5 and molecular weight 404.26 g/mol. IUPAC: [8-[2-(4-hydroxy-6-oxooxan-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylbutanoate.
Chemical Property Profile of 洛伐他汀
Property Insights of 洛伐他汀
The XLogP value of 4.3 indicates that 洛伐他汀 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 洛伐他汀. Following Lipinski's Rule of Five, 洛伐他汀 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 洛伐他汀?
The CAS number of 洛伐他汀 is 75330-75-5.
What is the molecular formula of 洛伐他汀?
The molecular formula of 洛伐他汀 is C24H36O5.
What is the molecular weight of 洛伐他汀?
The molecular weight of 洛伐他汀 is 404.26 g/mol.
Where can I buy 洛伐他汀?
You can request a quote for 洛伐他汀 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 洛伐他汀?
Yes, KEHONG BIO provides custom synthesis services for 洛伐他汀 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.