HF-25(OH)D3 structure

HF-25(OH)D3

TL;DR: HF-25(OH)D3 (CAS 75303-43-4) is a chemical compound with molecular formula C27H38F6O2 and molecular weight 508.28 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-7,7,7-trifluoro-6-hydroxy-6-(trifluoromethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

Also Known As: HF-25(OH)D3, J3.796.519G, 25-Hydroxy-26,26,26,27,27,27-hexafluorovitamin D3, (5Z,7E)-(3S)-26,26,26,27,27,27-hexafluoro-9,10-seco-5,7,10(19)-cholestatriene-3,25-diol, 26,26,26,27,27,27-hexafluoro-25-hydroxyvitamin D3 / 26,26,26,27,27,27-hexafluoro-25-hydroxycholecalciferol

CAS: 75303-43-4
Molecular Formula C27H38F6O2
Molecular Weight 508.28 g/mol
LogP 7.8187
Topological Polar Surface Area 40.46 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 2
Rotatable Bonds 6
Exact Mass 508.2776
Heavy Atoms 35
Complexity 825.58997

Chemical Identifiers

CAS Number 75303-43-4
SMILES C[C@H](CCCC(C(F)(F)F)(C(F)(F)F)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C

Product Overview

HF-25(OH)D3 (CAS 75303-43-4), with molecular formula C27H38F6O2 and molecular weight 508.28 g/mol. IUPAC: (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-7,7,7-trifluoro-6-hydroxy-6-(trifluoromethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of HF-25(OH)D3

XLogP
7.8187
TPSA (Topological Polar Surface Area)
40.46
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
2
Rotatable Bonds
6
Heavy Atoms
35
Complexity
825.58997
Exact Mass
508.2776
Monoisotopic Mass
508.2776
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of HF-25(OH)D3

The XLogP value of 7.8187 indicates that HF-25(OH)D3 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.46 Ų, HF-25(OH)D3 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, HF-25(OH)D3 has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of HF-25(OH)D3?

The CAS number of HF-25(OH)D3 is 75303-43-4.

What is the molecular formula of HF-25(OH)D3?

The molecular formula of HF-25(OH)D3 is C27H38F6O2.

What is the molecular weight of HF-25(OH)D3?

The molecular weight of HF-25(OH)D3 is 508.28 g/mol.

Where can I buy HF-25(OH)D3?

You can request a quote for HF-25(OH)D3 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for HF-25(OH)D3?

Yes, KEHONG BIO provides custom synthesis services for HF-25(OH)D3 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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