4-Hydroxy-13-cis-retinoic acid
TL;DR: 4-Hydroxy-13-cis-retinoic acid (CAS 75281-25-3) is a chemical compound with molecular formula C20H28O3 and molecular weight 316.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
9-(3-hydroxy-2,6,6-trimethylcyclohexen-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
Also Known As: rac all-trans, 4-Hydroxyretinoic acid, 4-Hydroxyisotretinoin, 4-Hydroxy-13-cis-retinoic acid, 9-cis-4-hydroxyretinoic acid
| Molecular Formula | C20H28O3 |
|---|---|
| Molecular Weight | 316.20 g/mol |
| LogP | 4.5 |
| Topological Polar Surface Area | 57.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 316.20386 |
| Heavy Atoms | 23 |
| Complexity | 598.0 |
Chemical Identifiers
| CAS Number | 75281-25-3 |
|---|---|
| SMILES | CC1=C(C(CCC1O)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C |
| InChIKey | KGUMXGDKXYTTEY-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
4-Hydroxy-13-cis-retinoic acid (CAS 75281-25-3), with molecular formula C20H28O3 and molecular weight 316.20 g/mol. IUPAC: 9-(3-hydroxy-2,6,6-trimethylcyclohexen-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid.
Chemical Property Profile of 4-Hydroxy-13-cis-retinoic acid
Property Insights of 4-Hydroxy-13-cis-retinoic acid
The XLogP value of 4.5 indicates that 4-Hydroxy-13-cis-retinoic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.5 Ų, 4-Hydroxy-13-cis-retinoic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Hydroxy-13-cis-retinoic acid has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Hydroxy-13-cis-retinoic acid?
The CAS number of 4-Hydroxy-13-cis-retinoic acid is 75281-25-3.
What is the molecular formula of 4-Hydroxy-13-cis-retinoic acid?
The molecular formula of 4-Hydroxy-13-cis-retinoic acid is C20H28O3.
What is the molecular weight of 4-Hydroxy-13-cis-retinoic acid?
The molecular weight of 4-Hydroxy-13-cis-retinoic acid is 316.20 g/mol.
Where can I buy 4-Hydroxy-13-cis-retinoic acid?
You can request a quote for 4-Hydroxy-13-cis-retinoic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Hydroxy-13-cis-retinoic acid?
Yes, KEHONG BIO provides custom synthesis services for 4-Hydroxy-13-cis-retinoic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.