洛伐他汀酸
TL;DR: 洛伐他汀酸 (CAS 75225-51-3) is a chemical compound with molecular formula C24H38O6 and molecular weight 422.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
洛伐他汀酸
(3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
Also Known As: Lovastatin acid, Mevinolinic acid, Monacolinic K acid, MSD 803 acid, lovestatin acid
| Molecular Formula | C24H38O6 |
|---|---|
| Molecular Weight | 422.27 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 104.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 11 |
| Exact Mass | 422.26685 |
| Heavy Atoms | 30 |
| Complexity | 654.0 |
Chemical Identifiers
| CAS Number | 75225-51-3 |
|---|---|
| SMILES | CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)C |
| InChIKey | QLJODMDSTUBWDW-BXMDZJJMSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
洛伐他汀酸 (CAS 75225-51-3), with molecular formula C24H38O6 and molecular weight 422.27 g/mol. IUPAC: (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid.
Chemical Property Profile of 洛伐他汀酸
Property Insights of 洛伐他汀酸
The XLogP value of 3.5 indicates that 洛伐他汀酸 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 洛伐他汀酸. Following Lipinski's Rule of Five, 洛伐他汀酸 has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 洛伐他汀酸?
The CAS number of 洛伐他汀酸 is 75225-51-3.
What is the molecular formula of 洛伐他汀酸?
The molecular formula of 洛伐他汀酸 is C24H38O6.
What is the molecular weight of 洛伐他汀酸?
The molecular weight of 洛伐他汀酸 is 422.27 g/mol.
Where can I buy 洛伐他汀酸?
You can request a quote for 洛伐他汀酸 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 洛伐他汀酸?
Yes, KEHONG BIO provides custom synthesis services for 洛伐他汀酸 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.