AMG-487 metabolite M1
TL;DR: AMG-487 metabolite M1 (CAS 752244-90-9) is a chemical compound with molecular formula C32H28F3N5O5 and molecular weight 619.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1-oxidopyridin-1-ium-3-yl)methyl]-2-[4-(trifluoromethoxy)phenyl]acetamide
Also Known As: AMG-487 metabolite M1, Benzeneacetamide, N-((1R)-1-(3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido(2,3-d)pyrimidin-2-yl)ethyl)-N-((1-oxido-3-pyridinyl)methyl)-4-(trifluoromethoxy)-, N-((1R)-1-(3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido(2,3-d)pyrimidin-2-yl)ethyl)-N-((1-oxido-3-pyridinyl)methyl)-4-(trifluoromethoxy)benzeneacetamide, (R)-3-((N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-2-(4-(trifluoromethoxy)phenyl)acetamido)methyl)pyridine 1-oxide
| Molecular Formula | C32H28F3N5O5 |
|---|---|
| Molecular Weight | 619.20 g/mol |
| LogP | 5.0439 |
| Topological Polar Surface Area | 113.49 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 10 |
| Exact Mass | 619.2042 |
| Heavy Atoms | 45 |
| Complexity | 1861.4802 |
Chemical Identifiers
| CAS Number | 752244-90-9 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2[C@@H](C)N(CC4=C[N+](=CC=C4)[O-])C(=O)CC5=CC=C(C=C5)OC(F)(F)F |
Product Overview
AMG-487 metabolite M1 (CAS 752244-90-9), with molecular formula C32H28F3N5O5 and molecular weight 619.20 g/mol. IUPAC: N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(1-oxidopyridin-1-ium-3-yl)methyl]-2-[4-(trifluoromethoxy)phenyl]acetamide.
Chemical Property Profile of AMG-487 metabolite M1
Property Insights of AMG-487 metabolite M1
The XLogP value of 5.0439 indicates that AMG-487 metabolite M1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 113.49 Ų falls within the moderate polarity range, balancing permeability and solubility for AMG-487 metabolite M1. Following Lipinski's Rule of Five, AMG-487 metabolite M1 has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AMG-487 metabolite M1?
The CAS number of AMG-487 metabolite M1 is 752244-90-9.
What is the molecular formula of AMG-487 metabolite M1?
The molecular formula of AMG-487 metabolite M1 is C32H28F3N5O5.
What is the molecular weight of AMG-487 metabolite M1?
The molecular weight of AMG-487 metabolite M1 is 619.20 g/mol.
Where can I buy AMG-487 metabolite M1?
You can request a quote for AMG-487 metabolite M1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AMG-487 metabolite M1?
Yes, KEHONG BIO provides custom synthesis services for AMG-487 metabolite M1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.