NCA-0424 free base structure

NCA-0424 free base

TL;DR: NCA-0424 free base (CAS 752177-51-8) is a chemical compound with molecular formula C20H22N4O2 and molecular weight 350.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-methyl-2-[(6-methylindolo[3,2-b]quinoxalin-4-yl)methylamino]propane-1,3-diol

Also Known As: NCA-0424 free base, 1,3-Propanediol, 2-methyl-2-(((6-methyl-6H-indolo(2,3-b)quinoxalin-4-yl)methyl)amino)-, 2-Methyl-2-(((6-methyl-6H-indolo(2,3-b)quinoxalin-4-yl)methyl)amino)-1,3-propanediol, 2-Methyl-2-(6-methyl-6H-indolo[2,3-b]quinoxaline-4-ylmethylamino)-1,3-propanediol, 2-methyl-2-[({6-methyl-6H-indolo[2,3-b]quinoxalin-4-yl}methyl)amino]propane-1,3-diol

CAS: 752177-51-8
Molecular Formula C20H22N4O2
Molecular Weight 350.17 g/mol
LogP 2.1076
Topological Polar Surface Area 83.2 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 5
Rotatable Bonds 5
Exact Mass 350.1743
Heavy Atoms 26
Complexity 1099.2606

Chemical Identifiers

CAS Number 752177-51-8
SMILES CC(CO)(CO)NCC1=C2C(=CC=C1)N=C3C4=CC=CC=C4N(C3=N2)C

Product Overview

NCA-0424 free base (CAS 752177-51-8), with molecular formula C20H22N4O2 and molecular weight 350.17 g/mol. IUPAC: 2-methyl-2-[(6-methylindolo[3,2-b]quinoxalin-4-yl)methylamino]propane-1,3-diol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of NCA-0424 free base

XLogP
2.1076
TPSA (Topological Polar Surface Area)
83.2
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
5
Rotatable Bonds
5
Heavy Atoms
26
Complexity
1099.2606
Exact Mass
350.1743
Monoisotopic Mass
350.1743
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of NCA-0424 free base

The XLogP value of 2.1076 suggests moderate lipophilicity, balancing water solubility and membrane permeability for NCA-0424 free base. The TPSA of 83.2 Ų falls within the moderate polarity range, balancing permeability and solubility for NCA-0424 free base. Following Lipinski's Rule of Five, NCA-0424 free base has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of NCA-0424 free base?

The CAS number of NCA-0424 free base is 752177-51-8.

What is the molecular formula of NCA-0424 free base?

The molecular formula of NCA-0424 free base is C20H22N4O2.

What is the molecular weight of NCA-0424 free base?

The molecular weight of NCA-0424 free base is 350.17 g/mol.

Where can I buy NCA-0424 free base?

You can request a quote for NCA-0424 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for NCA-0424 free base?

Yes, KEHONG BIO provides custom synthesis services for NCA-0424 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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