Talmapimod
TL;DR: Talmapimod (CAS 750646-72-1) is a chemical compound with molecular formula C27H30ClFN4O3 and molecular weight 512.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[6-chloro-5-[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine-1-carbonyl]-1-methylindol-3-yl]-N,N-dimethyl-2-oxoacetamide
Also Known As: Talmapimod, talmapimodum, Scios 469, SCIO 469, rac-Talmapimod
| Molecular Formula | C27H30ClFN4O3 |
|---|---|
| Molecular Weight | 512.20 g/mol |
| LogP | 3.9767 |
| Topological Polar Surface Area | 65.86 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 512.19904 |
| Heavy Atoms | 36 |
| Complexity | 1335.0325 |
Chemical Identifiers
| CAS Number | 750646-72-1 |
|---|---|
| SMILES | C[C@@H]1CN([C@H](CN1C(=O)C2=C(C=C3C(=C2)C(=CN3C)C(=O)C(=O)N(C)C)Cl)C)CC4=CC=C(C=C4)F |
Product Overview
Talmapimod (CAS 750646-72-1), with molecular formula C27H30ClFN4O3 and molecular weight 512.20 g/mol. IUPAC: 2-[6-chloro-5-[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine-1-carbonyl]-1-methylindol-3-yl]-N,N-dimethyl-2-oxoacetamide.
Chemical Property Profile of Talmapimod
Property Insights of Talmapimod
The XLogP value of 3.9767 indicates that Talmapimod is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.86 Ų falls within the moderate polarity range, balancing permeability and solubility for Talmapimod. Following Lipinski's Rule of Five, Talmapimod has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Talmapimod?
The CAS number of Talmapimod is 750646-72-1.
What is the molecular formula of Talmapimod?
The molecular formula of Talmapimod is C27H30ClFN4O3.
What is the molecular weight of Talmapimod?
The molecular weight of Talmapimod is 512.20 g/mol.
Where can I buy Talmapimod?
You can request a quote for Talmapimod directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Talmapimod?
Yes, KEHONG BIO provides custom synthesis services for Talmapimod and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.