SGC-CLK-1
TL;DR: SGC-CLK-1 (CAS 748142-15-6) is a chemical compound with molecular formula C19H15F3N6O2 and molecular weight 416.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(6-methoxypyrazolo[1,5-b]pyridazin-3-yl)-N-[3-methoxy-5-(trifluoromethyl)phenyl]pyrimidin-2-amine
Also Known As: SGC-CLK-1, pyrazolo[1,5-b]pyridazine deriv. 47, 4-(6-methoxypyrazolo[1,5-b]pyridazin-3-yl)-N-[3-methoxy-5-(trifluoromethyl)phenyl]pyrimidin-2-amine, N-(3-Methoxy-5-(trifluoromethyl)phenyl)-4-(6-methoxypyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine, N-[3-methoxy-5-(trifluoromethyl)phenyl]-4-{6-methoxypyrazolo[1,5-a]pyridazin-3-yl}pyrimidin-2-amine
| Molecular Formula | C19H15F3N6O2 |
|---|---|
| Molecular Weight | 416.12 g/mol |
| LogP | 3.9659 |
| Topological Polar Surface Area | 86.46 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 416.12085 |
| Heavy Atoms | 30 |
| Complexity | 1208.567 |
Chemical Identifiers
| CAS Number | 748142-15-6 |
|---|---|
| SMILES | COC1=NN2C(=C(C=N2)C3=NC(=NC=C3)NC4=CC(=CC(=C4)C(F)(F)F)OC)C=C1 |
Product Overview
SGC-CLK-1 (CAS 748142-15-6), with molecular formula C19H15F3N6O2 and molecular weight 416.12 g/mol. IUPAC: 4-(6-methoxypyrazolo[1,5-b]pyridazin-3-yl)-N-[3-methoxy-5-(trifluoromethyl)phenyl]pyrimidin-2-amine.
Chemical Property Profile of SGC-CLK-1
Property Insights of SGC-CLK-1
The XLogP value of 3.9659 indicates that SGC-CLK-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.46 Ų falls within the moderate polarity range, balancing permeability and solubility for SGC-CLK-1. Following Lipinski's Rule of Five, SGC-CLK-1 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of SGC-CLK-1?
The CAS number of SGC-CLK-1 is 748142-15-6.
What is the molecular formula of SGC-CLK-1?
The molecular formula of SGC-CLK-1 is C19H15F3N6O2.
What is the molecular weight of SGC-CLK-1?
The molecular weight of SGC-CLK-1 is 416.12 g/mol.
Where can I buy SGC-CLK-1?
You can request a quote for SGC-CLK-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for SGC-CLK-1?
Yes, KEHONG BIO provides custom synthesis services for SGC-CLK-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.