环格列酮
TL;DR: 环格列酮 (CAS 74772-77-3) is a chemical compound with molecular formula C18H23NO3S and molecular weight 333.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
环格列酮
5-[[4-[(1-methylcyclohexyl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Also Known As: ciglitazone, Ciglitizone, Ciglitazona, Ciglitazonum, Cizitazone
| Molecular Formula | C18H23NO3S |
|---|---|
| Molecular Weight | 333.14 g/mol |
| LogP | 4.8 |
| Topological Polar Surface Area | 80.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 333.13986 |
| Heavy Atoms | 23 |
| Complexity | 440.0 |
Chemical Identifiers
| CAS Number | 74772-77-3 |
|---|---|
| SMILES | CC1(CCCCC1)COC2=CC=C(C=C2)CC3C(=O)NC(=O)S3 |
| InChIKey | YZFWTZACSRHJQD-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
环格列酮 (CAS 74772-77-3), with molecular formula C18H23NO3S and molecular weight 333.14 g/mol. IUPAC: 5-[[4-[(1-methylcyclohexyl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of 环格列酮
Property Insights of 环格列酮
The XLogP value of 4.8 indicates that 环格列酮 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 环格列酮. Following Lipinski's Rule of Five, 环格列酮 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 环格列酮?
The CAS number of 环格列酮 is 74772-77-3.
What is the molecular formula of 环格列酮?
The molecular formula of 环格列酮 is C18H23NO3S.
What is the molecular weight of 环格列酮?
The molecular weight of 环格列酮 is 333.14 g/mol.
Where can I buy 环格列酮?
You can request a quote for 环格列酮 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 环格列酮?
Yes, KEHONG BIO provides custom synthesis services for 环格列酮 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.