N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide
TL;DR: N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide (CAS 74696-73-4) is a chemical compound with molecular formula C11H12F3NO2 and molecular weight 247.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl]propanamide
Also Known As: N-[4- phenyl]propionamide, N-[4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl]propanamide, 1-(4-Propionamido phenyl) 2,2,2-trifluoroethanol, N-(4-(1-Hydroxy-2,2,2-trifluoroethyl)phenyl)propanamide, N-[4-(2,2,2-TRIFLUORO-1-HYDROXYETHYL)PHENYL]PROPIONAMIDE
| Molecular Formula | C11H12F3NO2 |
|---|---|
| Molecular Weight | 247.08 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 247.08202 |
| Heavy Atoms | 17 |
| Complexity | 260.0 |
Chemical Identifiers
| CAS Number | 74696-73-4 |
|---|---|
| SMILES | CCC(=O)NC1=CC=C(C=C1)C(C(F)(F)F)O |
| InChIKey | NKBABNRRDTZGJV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide (CAS 74696-73-4), with molecular formula C11H12F3NO2 and molecular weight 247.08 g/mol. IUPAC: N-[4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl]propanamide.
Chemical Property Profile of N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide
Property Insights of N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide. With a topological polar surface area (TPSA) of 49.3 Ų, N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide?
The CAS number of N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide is 74696-73-4.
What is the molecular formula of N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide?
The molecular formula of N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide is C11H12F3NO2.
What is the molecular weight of N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide?
The molecular weight of N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide is 247.08 g/mol.
Where can I buy N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide?
You can request a quote for N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)propanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.