(E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide
TL;DR: (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide (CAS 74675-92-6) is a chemical compound with molecular formula C12H8ClN3O3S and molecular weight 309.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide
Also Known As: (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide, (E)-3-(2-chlorophenyl)-N-(5-nitrothiazol-2-yl)acrylamide, (2E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide, (E)-3-(2-CHLOROPHENYL)-N-(5-NITRO-1,3-THIAZOL-2-YL)-2-PROPENAMIDE
| Molecular Formula | C12H8ClN3O3S |
|---|---|
| Molecular Weight | 309.00 g/mol |
| LogP | 3.3566 |
| Topological Polar Surface Area | 85.13 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 308.9975 |
| Heavy Atoms | 20 |
| Complexity | 684.092 |
Chemical Identifiers
| CAS Number | 74675-92-6 |
|---|---|
| SMILES | C1=CC=C(C(=C1)/C=C/C(=O)NC2=NC=C(S2)[N+](=O)[O-])Cl |
Product Overview
(E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide (CAS 74675-92-6), with molecular formula C12H8ClN3O3S and molecular weight 309.00 g/mol. IUPAC: (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide.
Chemical Property Profile of (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide
Property Insights of (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide
The XLogP value of 3.3566 indicates that (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.13 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide. Following Lipinski's Rule of Five, (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide?
The CAS number of (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide is 74675-92-6.
What is the molecular formula of (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide?
The molecular formula of (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide is C12H8ClN3O3S.
What is the molecular weight of (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide?
The molecular weight of (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide is 309.00 g/mol.
Where can I buy (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide?
You can request a quote for (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(2-chlorophenyl)-N-(5-nitro-1,3-thiazol-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.