![5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine structure](/static/products/746/746607-85-2.png)
5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine
TL;DR: 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine (CAS 746607-85-2) is a chemical compound with molecular formula C8H3F6N3S and molecular weight 287.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5,7-bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine
Also Known As: thiazolo[4,5-b]pyridin-2-amine,5,7-bis(trifluoromethyl)-, 5,7-bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine
| Molecular Formula | C8H3F6N3S |
|---|---|
| Molecular Weight | 287.00 g/mol |
| LogP | 3.3111 |
| Topological Polar Surface Area | 51.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 0 |
| Exact Mass | 286.99518 |
| Heavy Atoms | 18 |
| Complexity | 599.1237 |
Chemical Identifiers
| CAS Number | 746607-85-2 |
|---|---|
| SMILES | C1=C(C2=C(N=C1C(F)(F)F)N=C(S2)N)C(F)(F)F |
Product Overview
5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine (CAS 746607-85-2), with molecular formula C8H3F6N3S and molecular weight 287.00 g/mol. IUPAC: 5,7-bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine.
Chemical Property Profile of 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine
Property Insights of 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine
The XLogP value of 3.3111 indicates that 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.8 Ų, 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine?
The CAS number of 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine is 746607-85-2.
What is the molecular formula of 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine?
The molecular formula of 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine is C8H3F6N3S.
What is the molecular weight of 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine?
The molecular weight of 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine is 287.00 g/mol.
Where can I buy 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine?
You can request a quote for 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 5,7-Bis(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.