7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one
TL;DR: 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one (CAS 74527-40-5) is a chemical compound with molecular formula C14H8F3NO3S and molecular weight 327.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-methoxy-3-(1,3-thiazol-4-yl)-2-(trifluoromethyl)chromen-4-one
Also Known As: IFLab1_000483, IDI1_008702, 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one, 7-methoxy-3-(1,3-thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one, 7-methoxy-3-(1,3-thiazol-4-yl)-2-(trifluoromethyl)chromen-4-one
| Molecular Formula | C14H8F3NO3S |
|---|---|
| Molecular Weight | 327.02 g/mol |
| LogP | 3.1 |
| Topological Polar Surface Area | 76.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 327.0177 |
| Heavy Atoms | 22 |
| Complexity | 494.0 |
Chemical Identifiers
| CAS Number | 74527-40-5 |
|---|---|
| SMILES | COC1=CC2=C(C=C1)C(=O)C(=C(O2)C(F)(F)F)C3=CSC=N3 |
| InChIKey | GRBMCEDXNPSULL-UHFFFAOYSA-N |
Product Overview
7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one (CAS 74527-40-5), with molecular formula C14H8F3NO3S and molecular weight 327.02 g/mol. IUPAC: 7-methoxy-3-(1,3-thiazol-4-yl)-2-(trifluoromethyl)chromen-4-one.
Chemical Property Profile of 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one
Property Insights of 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one
The XLogP value of 3.1 indicates that 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one. Following Lipinski's Rule of Five, 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one?
The CAS number of 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one is 74527-40-5.
What is the molecular formula of 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one?
The molecular formula of 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one is C14H8F3NO3S.
What is the molecular weight of 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one?
The molecular weight of 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one is 327.02 g/mol.
Where can I buy 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one?
You can request a quote for 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one?
Yes, KEHONG BIO provides custom synthesis services for 7-methoxy-3-(thiazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.