Diglycyl-histidine structure

Diglycyl-histidine

TL;DR: Diglycyl-histidine (CAS 7451-76-5) is a chemical compound with molecular formula C10H15N5O4 and molecular weight 269.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoic acid

Also Known As: Gly-gly-his, Diglycyl-histidine, diglycylhistidine, H-Gly-Gly-His-OH, Glycylglycyl-L-histidine

CAS: 7451-76-5
Molecular Formula C10H15N5O4
Molecular Weight 269.11 g/mol
LogP -4.5
Topological Polar Surface Area 150.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 6
Rotatable Bonds 7
Exact Mass 269.1124
Heavy Atoms 19
Complexity 349.0

Chemical Identifiers

CAS Number 7451-76-5
SMILES C1=C(NC=N1)CC(C(=O)O)NC(=O)CNC(=O)CN
InChIKey PDAWDNVHMUKWJR-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (6 patents) Organic Building Blocks (2 patents) Peptides & Amino Acids (7 patents) Pharmaceutical Intermediates (18 patents) Specialty Chemicals (5 patents)

Product Overview

Diglycyl-histidine (CAS 7451-76-5), with molecular formula C10H15N5O4 and molecular weight 269.11 g/mol. IUPAC: 2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Diglycyl-histidine

XLogP
-4.5
TPSA (Topological Polar Surface Area)
150.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
6
Rotatable Bonds
7
Heavy Atoms
19
Complexity
349.0
Exact Mass
269.1124
Monoisotopic Mass
269.1124
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Diglycyl-histidine

The XLogP value of -4.5 indicates that Diglycyl-histidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 150.0 Ų indicates high polarity, suggesting Diglycyl-histidine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Diglycyl-histidine has 5 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Diglycyl-histidine?

The CAS number of Diglycyl-histidine is 7451-76-5.

What is the molecular formula of Diglycyl-histidine?

The molecular formula of Diglycyl-histidine is C10H15N5O4.

What is the molecular weight of Diglycyl-histidine?

The molecular weight of Diglycyl-histidine is 269.11 g/mol.

Where can I buy Diglycyl-histidine?

You can request a quote for Diglycyl-histidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Diglycyl-histidine?

Yes, KEHONG BIO provides custom synthesis services for Diglycyl-histidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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