Copper bleomycin structure

Copper bleomycin

TL;DR: Copper bleomycin (CAS 7451-53-8) is a chemical compound with molecular formula C55H81CuN17O21S3 and molecular weight 1474.42 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

copper 3-[4-amino-6-[[1-[3-[3,5-dihydroxy-6-(hydroxymethyl)-4-(C-oxidocarbonimidoyl)oxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[[5-[[1-[2-[4-[4-(3-dimethylsulfoniopropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]carbamoyl]-5-methylpyrimidin-2-yl]-3-[(2-amino-3-imino-3-oxidopropyl)amino]propanimidate

Also Known As: Copper bleomycin, bleomycin Cu, Bleomycin A2-copper(II) complex, Bleomycinamide, N1-(3-(dimethylsulfonio)propyl)-, copper complex, Copper(2+), (N1-(3-(dimethylsulfonio)propyl)bleomycinamidato)-

CAS: 7451-53-8
Molecular Formula C55H81CuN17O21S3
Molecular Weight 1474.42 g/mol
LogP -8.78517
Topological Polar Surface Area 696.0 Ų
Hydrogen Bond Donors 20
Hydrogen Bond Acceptors 34
Rotatable Bonds 36
Exact Mass 1474.425
Heavy Atoms 97
Complexity 2580.0

Chemical Identifiers

CAS Number 7451-53-8
SMILES CC1=C(N=C(N=C1N)C(CC(=N)[O-])NCC(C(=N)[O-])N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=N)[O-])O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.[Cu+2]
InChIKey OPSYKRSMSZOFSX-UHFFFAOYSA-L

Product Overview

Copper bleomycin (CAS 7451-53-8), with molecular formula C55H81CuN17O21S3 and molecular weight 1474.42 g/mol. IUPAC: copper 3-[4-amino-6-[[1-[3-[3,5-dihydroxy-6-(hydroxymethyl)-4-(C-oxidocarbonimidoyl)oxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[[5-[[1-[2-[4-[4-(3-dimethylsulfoniopropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]carbamoyl]-5-methylpyrimidin-2-yl]-3-[(2-amino-3-imino-3-oxidopropyl)amino]propanimidate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Copper bleomycin

XLogP
-8.78517
TPSA (Topological Polar Surface Area)
696.0
Hydrogen Bond Donors
20
Hydrogen Bond Acceptors
34
Rotatable Bonds
36
Heavy Atoms
97
Complexity
2580.0
Exact Mass
1474.425
Monoisotopic Mass
1474.425
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Copper bleomycin

The XLogP value of -8.78517 indicates that Copper bleomycin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 696.0 Ų indicates high polarity, suggesting Copper bleomycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Copper bleomycin has 20 hydrogen bond donor(s) and 34 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Copper bleomycin?

The CAS number of Copper bleomycin is 7451-53-8.

What is the molecular formula of Copper bleomycin?

The molecular formula of Copper bleomycin is C55H81CuN17O21S3.

What is the molecular weight of Copper bleomycin?

The molecular weight of Copper bleomycin is 1474.42 g/mol.

Where can I buy Copper bleomycin?

You can request a quote for Copper bleomycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Copper bleomycin?

Yes, KEHONG BIO provides custom synthesis services for Copper bleomycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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