前列腺素E1
TL;DR: 前列腺素E1 (CAS 745-65-3) is a chemical compound with molecular formula C20H34O5 and molecular weight 354.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
前列腺素E1
7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxocyclopentyl]heptanoic acid
Also Known As: alprostadil, Prostaglandin E1, Topiglan, Ovinonic acid, 8-iso Prostaglandin E1
| Molecular Formula | C20H34O5 |
|---|---|
| Molecular Weight | 354.24 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 13 |
| Exact Mass | 354.24063 |
| Heavy Atoms | 25 |
| Complexity | 432.0 |
Chemical Identifiers
| CAS Number | 745-65-3 |
|---|---|
| SMILES | CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O |
| InChIKey | GMVPRGQOIOIIMI-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
前列腺素E1 (CAS 745-65-3), with molecular formula C20H34O5 and molecular weight 354.24 g/mol. IUPAC: 7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxocyclopentyl]heptanoic acid.
Chemical Property Profile of 前列腺素E1
Property Insights of 前列腺素E1
The XLogP value of 3.2 indicates that 前列腺素E1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 前列腺素E1. Following Lipinski's Rule of Five, 前列腺素E1 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 前列腺素E1?
The CAS number of 前列腺素E1 is 745-65-3.
What is the molecular formula of 前列腺素E1?
The molecular formula of 前列腺素E1 is C20H34O5.
What is the molecular weight of 前列腺素E1?
The molecular weight of 前列腺素E1 is 354.24 g/mol.
Where can I buy 前列腺素E1?
You can request a quote for 前列腺素E1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 前列腺素E1?
Yes, KEHONG BIO provides custom synthesis services for 前列腺素E1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.