N-Trimethylsilyl-N-methylacetamide
TL;DR: N-Trimethylsilyl-N-methylacetamide (CAS 7449-74-3) is a chemical compound with molecular formula C6H15NOSi and molecular weight 145.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-methyl-N-trimethylsilylacetamide
Also Known As: N-Methyl-N-(trimethylsilyl)acetamide, N-Methyl-N-trimethylsilylacetamide, Acetamide, N-methyl-N-(trimethylsilyl)-, N-Methyl-N-TMS-acetamide, N-Trimethylsilyl-N-methylacetamide
| Molecular Formula | C6H15NOSi |
|---|---|
| Molecular Weight | 145.09 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 20.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 145.09229 |
| Heavy Atoms | 9 |
| Complexity | 117.0 |
Chemical Identifiers
| CAS Number | 7449-74-3 |
|---|---|
| SMILES | CC(=O)N(C)[Si](C)(C)C |
| InChIKey | QHUOBLDKFGCVCG-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 18 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N-Trimethylsilyl-N-methylacetamide (CAS 7449-74-3), with molecular formula C6H15NOSi and molecular weight 145.09 g/mol. IUPAC: N-methyl-N-trimethylsilylacetamide.
Chemical Property Profile of N-Trimethylsilyl-N-methylacetamide
Property Insights of N-Trimethylsilyl-N-methylacetamide
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-Trimethylsilyl-N-methylacetamide. With a topological polar surface area (TPSA) of 20.3 Ų, N-Trimethylsilyl-N-methylacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-Trimethylsilyl-N-methylacetamide has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Trimethylsilyl-N-methylacetamide?
The CAS number of N-Trimethylsilyl-N-methylacetamide is 7449-74-3.
What is the molecular formula of N-Trimethylsilyl-N-methylacetamide?
The molecular formula of N-Trimethylsilyl-N-methylacetamide is C6H15NOSi.
What is the molecular weight of N-Trimethylsilyl-N-methylacetamide?
The molecular weight of N-Trimethylsilyl-N-methylacetamide is 145.09 g/mol.
Where can I buy N-Trimethylsilyl-N-methylacetamide?
You can request a quote for N-Trimethylsilyl-N-methylacetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Trimethylsilyl-N-methylacetamide?
Yes, KEHONG BIO provides custom synthesis services for N-Trimethylsilyl-N-methylacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.