![2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide structure](/static/products/744/744229-71-8.png)
2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide
TL;DR: 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide (CAS 744229-71-8) is a chemical compound with molecular formula C23H25N3O5S and molecular weight 455.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-(3-piperidin-1-ylsulfonylphenyl)prop-2-enamide
Also Known As: 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide, (E)-2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-(3-piperidin-1-ylsulfonylphenyl)prop-2-enamide, 2-cyano-3-(3-ethoxy-4-hydroxy-phenyl)-N-[3-(1-piperidylsulfonyl)phenyl]prop-2-enamide
| Molecular Formula | C23H25N3O5S |
|---|---|
| Molecular Weight | 455.15 g/mol |
| LogP | 3.51118 |
| Topological Polar Surface Area | 119.73 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 455.1515 |
| Heavy Atoms | 32 |
| Complexity | 1162.3947 |
Chemical Identifiers
| CAS Number | 744229-71-8 |
|---|---|
| SMILES | CCOC1=C(C=CC(=C1)/C=C(\C#N)/C(=O)NC2=CC(=CC=C2)S(=O)(=O)N3CCCCC3)O |
Product Overview
2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide (CAS 744229-71-8), with molecular formula C23H25N3O5S and molecular weight 455.15 g/mol. IUPAC: (E)-2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-(3-piperidin-1-ylsulfonylphenyl)prop-2-enamide.
Chemical Property Profile of 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide
Property Insights of 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide
The XLogP value of 3.51118 indicates that 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 119.73 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide. Following Lipinski's Rule of Five, 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide?
The CAS number of 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide is 744229-71-8.
What is the molecular formula of 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide?
The molecular formula of 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide is C23H25N3O5S.
What is the molecular weight of 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide?
The molecular weight of 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide is 455.15 g/mol.
Where can I buy 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide?
You can request a quote for 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for 2-cyano-3-(3-ethoxy-4-hydroxyphenyl)-N-[3-(piperidine-1-sulfonyl)phenyl]prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.