1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester structure

1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester

TL;DR: 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester (CAS 74381-42-3) is a chemical compound with molecular formula C13H17NO2Si and molecular weight 247.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

trimethylsilyl 1-methylindole-2-carboxylate

Also Known As: trimethylsilyl 1-methylindole-2-carboxylate, Trimethylsilyl 1-methyl-1H-indole-2-carboxylate, 1-Methylindole-2-carboxylic acid, TMS derivative, 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester, Trimethylsilyl 1-methyl-1H-indole-2-carboxylate #

CAS: 74381-42-3
Molecular Formula C13H17NO2Si
Molecular Weight 247.10 g/mol
LogP 3.17
Topological Polar Surface Area 31.2 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 3
Exact Mass 247.10286
Heavy Atoms 17
Complexity 300.0

Chemical Identifiers

CAS Number 74381-42-3
SMILES CN1C2=CC=CC=C2C=C1C(=O)O[Si](C)(C)C
InChIKey DMFZMCPFVIWFNQ-UHFFFAOYSA-N

Product Overview

1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester (CAS 74381-42-3), with molecular formula C13H17NO2Si and molecular weight 247.10 g/mol. IUPAC: trimethylsilyl 1-methylindole-2-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester

XLogP
3.17
TPSA (Topological Polar Surface Area)
31.2
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
3
Heavy Atoms
17
Complexity
300.0
Exact Mass
247.10286
Monoisotopic Mass
247.10286
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester

The XLogP value of 3.17 indicates that 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 31.2 Ų, 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester?

The CAS number of 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester is 74381-42-3.

What is the molecular formula of 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester?

The molecular formula of 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester is C13H17NO2Si.

What is the molecular weight of 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester?

The molecular weight of 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester is 247.10 g/mol.

Where can I buy 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester?

You can request a quote for 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester?

Yes, KEHONG BIO provides custom synthesis services for 1H-Indole-2-carboxylic acid, 1-methyl-, trimethylsilyl ester and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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