1H-Indole-3-acetonitrile, 1-(trimethylsilyl)-
TL;DR: 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- (CAS 74367-49-0) is a chemical compound with molecular formula C13H16N2Si and molecular weight 228.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(1-trimethylsilylindol-3-yl)acetonitrile
Also Known As: Indole-3-acetonitrile, TMS, 1h-indole-3-acetonitrile,1-, 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)-, 1H-Indole-3-acetonitrile,1- -, Indole-3-acetonitrile, TMS derivative
| Molecular Formula | C13H16N2Si |
|---|---|
| Molecular Weight | 228.11 g/mol |
| LogP | 3.39038 |
| Topological Polar Surface Area | 28.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 228.10828 |
| Heavy Atoms | 16 |
| Complexity | 299.0 |
Chemical Identifiers
| CAS Number | 74367-49-0 |
|---|---|
| SMILES | C[Si](C)(C)N1C=C(C2=CC=CC=C21)CC#N |
| InChIKey | QIPOVLUFFYDMLH-UHFFFAOYSA-N |
Product Overview
1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- (CAS 74367-49-0), with molecular formula C13H16N2Si and molecular weight 228.11 g/mol. IUPAC: 2-(1-trimethylsilylindol-3-yl)acetonitrile.
Chemical Property Profile of 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)-
Property Insights of 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)-
The XLogP value of 3.39038 indicates that 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.7 Ų, 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)-?
The CAS number of 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- is 74367-49-0.
What is the molecular formula of 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)-?
The molecular formula of 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- is C13H16N2Si.
What is the molecular weight of 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)-?
The molecular weight of 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- is 228.11 g/mol.
Where can I buy 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)-?
You can request a quote for 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)-?
Yes, KEHONG BIO provides custom synthesis services for 1H-Indole-3-acetonitrile, 1-(trimethylsilyl)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.