1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester
TL;DR: 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester (CAS 74367-41-2) is a chemical compound with molecular formula C14H19NO2Si and molecular weight 261.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 1-trimethylsilylindole-2-carboxylate
Also Known As: ethyl 1-trimethylsilylindole-2-carboxylate, Ethyl indole-2-carboxylate, TMS derivative, Ethyl 1-(trimethylsilyl)-1H-indole-2-carboxylate, 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester, Ethyl 1-(trimethylsilyl)-1H-indole-2-carboxylate #
| Molecular Formula | C14H19NO2Si |
|---|---|
| Molecular Weight | 261.12 g/mol |
| LogP | 3.501 |
| Topological Polar Surface Area | 31.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 261.1185 |
| Heavy Atoms | 18 |
| Complexity | 313.0 |
Chemical Identifiers
| CAS Number | 74367-41-2 |
|---|---|
| SMILES | CCOC(=O)C1=CC2=CC=CC=C2N1[Si](C)(C)C |
| InChIKey | BMEFDGCRVFIDNN-UHFFFAOYSA-N |
Product Overview
1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester (CAS 74367-41-2), with molecular formula C14H19NO2Si and molecular weight 261.12 g/mol. IUPAC: ethyl 1-trimethylsilylindole-2-carboxylate.
Chemical Property Profile of 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester
Property Insights of 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester
The XLogP value of 3.501 indicates that 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 31.2 Ų, 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester?
The CAS number of 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester is 74367-41-2.
What is the molecular formula of 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester?
The molecular formula of 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester is C14H19NO2Si.
What is the molecular weight of 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester?
The molecular weight of 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester is 261.12 g/mol.
Where can I buy 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester?
You can request a quote for 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester?
Yes, KEHONG BIO provides custom synthesis services for 1H-Indole-2-carboxylic acid, 1-(trimethylsilyl)-, ethyl ester and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.