5-Fluorouracil glucuronamide
TL;DR: 5-Fluorouracil glucuronamide (CAS 74240-89-4) is a chemical compound with molecular formula C10H12FN3O7 and molecular weight 305.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,3S,4S,5R,6R)-6-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4,5-trihydroxyoxane-2-carboxamide
Also Known As: 5-fluorouracil Glucuronamide, 5-fluorouracilglucuronamide, MG 6812, (2S,3S,4S,5R,6R)-6-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4,5-trihydroxyoxane-2-carboxamide, 1-Deossi-1-(3,4-diidro-2,4-diosso-5-fluoro-1(2H)pirimidinil)glucopiranuronamide [Italian]
| Molecular Formula | C10H12FN3O7 |
|---|---|
| Molecular Weight | 305.07 g/mol |
| LogP | -3.0 |
| Topological Polar Surface Area | 162.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 305.06592 |
| Heavy Atoms | 21 |
| Complexity | 525.0 |
Chemical Identifiers
| CAS Number | 74240-89-4 |
|---|---|
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)N)O)O)O)F |
| InChIKey | PERCEIMMBVMDHG-HYMLEYLXSA-N |
Product Overview
5-Fluorouracil glucuronamide (CAS 74240-89-4), with molecular formula C10H12FN3O7 and molecular weight 305.07 g/mol. IUPAC: (2S,3S,4S,5R,6R)-6-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4,5-trihydroxyoxane-2-carboxamide.
Chemical Property Profile of 5-Fluorouracil glucuronamide
Property Insights of 5-Fluorouracil glucuronamide
The XLogP value of -3.0 indicates that 5-Fluorouracil glucuronamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 162.0 Ų indicates high polarity, suggesting 5-Fluorouracil glucuronamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-Fluorouracil glucuronamide has 5 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Fluorouracil glucuronamide?
The CAS number of 5-Fluorouracil glucuronamide is 74240-89-4.
What is the molecular formula of 5-Fluorouracil glucuronamide?
The molecular formula of 5-Fluorouracil glucuronamide is C10H12FN3O7.
What is the molecular weight of 5-Fluorouracil glucuronamide?
The molecular weight of 5-Fluorouracil glucuronamide is 305.07 g/mol.
Where can I buy 5-Fluorouracil glucuronamide?
You can request a quote for 5-Fluorouracil glucuronamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Fluorouracil glucuronamide?
Yes, KEHONG BIO provides custom synthesis services for 5-Fluorouracil glucuronamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.