Isavuconazonium structure

Isavuconazonium

TL;DR: Isavuconazonium (CAS 742049-41-8) is a chemical compound with molecular formula C35H35F2N8O5S+ and molecular weight 717.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[2-[1-[1-[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1,2,4-triazol-4-ium-4-yl]ethoxycarbonyl-methylamino]-3-pyridinyl]methyl 2-(methylamino)acetate

Also Known As: Isavuconazonium, Isavuconazonium ion, Cresemba, Isavuconazonium cation, Isavuconazonium [USAN]

CAS: 742049-41-8
Molecular Formula C35H35F2N8O5S+
Molecular Weight 717.24 g/mol
LogP 4.58458
Topological Polar Surface Area 159.37 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 11
Rotatable Bonds 13
Exact Mass 717.24194
Heavy Atoms 51
Complexity 2050.0469

Chemical Identifiers

CAS Number 742049-41-8
SMILES C[C@@H](C1=NC(=CS1)C2=CC=C(C=C2)C#N)[C@](CN3C=[N+](C=N3)C(C)OC(=O)N(C)C4=C(C=CC=N4)COC(=O)CNC)(C5=C(C=CC(=C5)F)F)O

Product Overview

Isavuconazonium (CAS 742049-41-8), with molecular formula C35H35F2N8O5S+ and molecular weight 717.24 g/mol. IUPAC: [2-[1-[1-[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1,2,4-triazol-4-ium-4-yl]ethoxycarbonyl-methylamino]-3-pyridinyl]methyl 2-(methylamino)acetate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Isavuconazonium

XLogP
4.58458
TPSA (Topological Polar Surface Area)
159.37
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
11
Rotatable Bonds
13
Heavy Atoms
51
Complexity
2050.0469
Exact Mass
717.24194
Monoisotopic Mass
717.24194
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Isavuconazonium

The XLogP value of 4.58458 indicates that Isavuconazonium is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 159.37 Ų indicates high polarity, suggesting Isavuconazonium may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Isavuconazonium has 2 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Isavuconazonium?

The CAS number of Isavuconazonium is 742049-41-8.

What is the molecular formula of Isavuconazonium?

The molecular formula of Isavuconazonium is C35H35F2N8O5S+.

What is the molecular weight of Isavuconazonium?

The molecular weight of Isavuconazonium is 717.24 g/mol.

Where can I buy Isavuconazonium?

You can request a quote for Isavuconazonium directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Isavuconazonium?

Yes, KEHONG BIO provides custom synthesis services for Isavuconazonium and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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