多沙唑嗪
TL;DR: 多沙唑嗪 (CAS 74191-85-8) is a chemical compound with molecular formula C23H25N5O5 and molecular weight 451.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
多沙唑嗪
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Also Known As: doxazosin, Doxazosine, Doxazosinum, Doxazosina, Doxazosin mesylate
| Molecular Formula | C23H25N5O5 |
|---|---|
| Molecular Weight | 451.19 g/mol |
| LogP | 2.5 |
| Topological Polar Surface Area | 112.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 451.18558 |
| Heavy Atoms | 33 |
| Complexity | 678.0 |
| Melting Point | 275-277 |
| Boiling Point | 718 |
| Solubility | 0.8% |
Chemical Identifiers
| CAS Number | 74191-85-8 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC |
| InChIKey | RUZYUOTYCVRMRZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 21 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
多沙唑嗪 (CAS 74191-85-8), with molecular formula C23H25N5O5 and molecular weight 451.19 g/mol. IUPAC: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone.
Chemical Property Profile of 多沙唑嗪
Property Insights of 多沙唑嗪
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 多沙唑嗪. The TPSA of 112.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 多沙唑嗪. Following Lipinski's Rule of Five, 可迅 has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 可迅?
The CAS number of 可迅 is 74191-85-8.
What is the molecular formula of 可迅?
The molecular formula of 可迅 is C23H25N5O5.
What is the molecular weight of 可迅?
The molecular weight of 可迅 is 451.19 g/mol.
Where can I buy 可迅?
You can request a quote for 可迅 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 可迅?
Yes, KEHONG BIO provides custom synthesis services for 可迅 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.