Alfaprostol structure

Alfaprostol

TL;DR: Alfaprostol (CAS 74176-31-1) is a chemical compound with molecular formula C24H38O5 and molecular weight 406.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

methyl (Z)-7-[(1R,3R,5S)-2-[(3S)-5-cyclohexyl-3-hydroxypent-1-ynyl]-3,5-dihydroxycyclopentyl]hept-5-enoate

Also Known As: Alfaprostol, Alfaprostolum [INN-Latin], Alfaprostol [USAN:BAN:INN], EINECS 277-746-0, Ro 22-9000

CAS: 74176-31-1
Molecular Formula C24H38O5
Molecular Weight 406.27 g/mol
LogP 3.3587
Topological Polar Surface Area 86.99 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 5
Rotatable Bonds 9
Exact Mass 406.2719
Heavy Atoms 29
Complexity 569.5554

Chemical Identifiers

CAS Number 74176-31-1
SMILES COC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H](C1C#C[C@H](CCC2CCCCC2)O)O)O

Product Overview

Alfaprostol (CAS 74176-31-1), with molecular formula C24H38O5 and molecular weight 406.27 g/mol. IUPAC: methyl (Z)-7-[(1R,3R,5S)-2-[(3S)-5-cyclohexyl-3-hydroxypent-1-ynyl]-3,5-dihydroxycyclopentyl]hept-5-enoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Alfaprostol

XLogP
3.3587
TPSA (Topological Polar Surface Area)
86.99
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
5
Rotatable Bonds
9
Heavy Atoms
29
Complexity
569.5554
Exact Mass
406.2719
Monoisotopic Mass
406.2719
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Alfaprostol

The XLogP value of 3.3587 indicates that Alfaprostol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.99 Ų falls within the moderate polarity range, balancing permeability and solubility for Alfaprostol. Following Lipinski's Rule of Five, Alfaprostol has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Alfaprostol?

The CAS number of Alfaprostol is 74176-31-1.

What is the molecular formula of Alfaprostol?

The molecular formula of Alfaprostol is C24H38O5.

What is the molecular weight of Alfaprostol?

The molecular weight of Alfaprostol is 406.27 g/mol.

Where can I buy Alfaprostol?

You can request a quote for Alfaprostol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Alfaprostol?

Yes, KEHONG BIO provides custom synthesis services for Alfaprostol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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