Lormetazepam glucuronide
TL;DR: Lormetazepam glucuronide (CAS 74140-65-1) is a chemical compound with molecular formula C22H20Cl2N2O8 and molecular weight 510.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,3S,4S,5R,6S)-6-[[7-chloro-5-(2-chlorophenyl)-1-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
Also Known As: Lormetazepam glucuronide, N(1),N(8)-Bis(gamma-glutamyl)spermidine, (2S,3S,4S,5R,6S)-6-[[7-chloro-5-(2-chlorophenyl)-1-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid, beta-D-Glucopyranosiduronic acid, 7-chloro-5-(12-chlorophenyl)-2,3-dihydro-1-methyl-2-oxo-1H-1,4-benzodiazepin-3-yl, (2S,3S,4S,5R,6S)-6-((7-chloro-5-(2-chlorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
| Molecular Formula | C22H20Cl2N2O8 |
|---|---|
| Molecular Weight | 510.06 g/mol |
| LogP | 1.1 |
| Topological Polar Surface Area | 149.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 510.05966 |
| Heavy Atoms | 34 |
| Complexity | 816.0 |
Chemical Identifiers
| CAS Number | 74140-65-1 |
|---|---|
| SMILES | CN1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O)C4=CC=CC=C4Cl |
| InChIKey | NBILRGWHLWNKBM-RYQNVSPKSA-N |
Product Overview
Lormetazepam glucuronide (CAS 74140-65-1), with molecular formula C22H20Cl2N2O8 and molecular weight 510.06 g/mol. IUPAC: (2S,3S,4S,5R,6S)-6-[[7-chloro-5-(2-chlorophenyl)-1-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.
Chemical Property Profile of Lormetazepam glucuronide
Property Insights of Lormetazepam glucuronide
The XLogP value of 1.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Lormetazepam glucuronide. The TPSA of 149.0 Ų indicates high polarity, suggesting Lormetazepam glucuronide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Lormetazepam glucuronide has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lormetazepam glucuronide?
The CAS number of Lormetazepam glucuronide is 74140-65-1.
What is the molecular formula of Lormetazepam glucuronide?
The molecular formula of Lormetazepam glucuronide is C22H20Cl2N2O8.
What is the molecular weight of Lormetazepam glucuronide?
The molecular weight of Lormetazepam glucuronide is 510.06 g/mol.
Where can I buy Lormetazepam glucuronide?
You can request a quote for Lormetazepam glucuronide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lormetazepam glucuronide?
Yes, KEHONG BIO provides custom synthesis services for Lormetazepam glucuronide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.