Thr8-saralasin
TL;DR: Thr8-saralasin (CAS 74127-89-2) is a chemical compound with molecular formula C43H67N13O11 and molecular weight 941.51 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(4H-imidazol-4-yl)propanoyl] (2S,3R)-3-hydroxy-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoate
Also Known As: Thr8-saralasin, [(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(4H-imidazol-4-yl)propanoyl] (2S,3R)-3-hydroxy-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoate, Angiotensin II, 1-(N-methylglycine)-5-L-valine-8-L-threonine-, Silane, (phenylenedi-2,1-ethanediyl)bis(chlorodimethyl-, L-Threonine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-prolyl- 8
| Molecular Formula | C43H67N13O11 |
|---|---|
| Molecular Weight | 941.51 g/mol |
| LogP | -1.3 |
| Topological Polar Surface Area | 372.0 Ų |
| Hydrogen Bond Donors | 12 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 28 |
| Exact Mass | 941.5083 |
| Heavy Atoms | 67 |
| Complexity | 1800.0 |
Chemical Identifiers
| CAS Number | 74127-89-2 |
|---|---|
| SMILES | C[C@H]([C@@H](C(=O)OC(=O)[C@H](CC1C=NC=N1)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)NC(=O)[C@@H]3CCCN3)O |
| InChIKey | PUHVDWPGYSQGRB-MNMHTRMISA-N |
Product Overview
Thr8-saralasin (CAS 74127-89-2), with molecular formula C43H67N13O11 and molecular weight 941.51 g/mol. IUPAC: [(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(4H-imidazol-4-yl)propanoyl] (2S,3R)-3-hydroxy-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoate.
Chemical Property Profile of Thr8-saralasin
Property Insights of Thr8-saralasin
The XLogP value of -1.3 indicates that Thr8-saralasin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 372.0 Ų indicates high polarity, suggesting Thr8-saralasin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thr8-saralasin has 12 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thr8-saralasin?
The CAS number of Thr8-saralasin is 74127-89-2.
What is the molecular formula of Thr8-saralasin?
The molecular formula of Thr8-saralasin is C43H67N13O11.
What is the molecular weight of Thr8-saralasin?
The molecular weight of Thr8-saralasin is 941.51 g/mol.
Where can I buy Thr8-saralasin?
You can request a quote for Thr8-saralasin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thr8-saralasin?
Yes, KEHONG BIO provides custom synthesis services for Thr8-saralasin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.